Delayed and often impaired wound healing in the elderly presents major medical and
socioeconomic challenges. A comprehensive understanding of the cellular/molecular …

Abstract Background Mesenchymal stromal cells (MSCs) show great potential for
immunomodulatory and anti-inflammatory treatments. Clinical trials have been performed for …

Human mesenchymal stromal cells (hMSCs) seeded on calcium phosphate (CaP)
bioceramics are extensively explored in bone tissue engineering and have recently shown …

The regenerative capacity of mesenchymal stem cells (MSCs) is now attributed to their
ability to release paracrine factors into the extracellular matrix that boost tissue regeneration …

Foreign body giant cells (FBGCs) are crucial in the foreign body reaction at the biomaterial-
tissue interface, forming through the fusion of cells from the monocyte/macrophage lineage …

Bone regeneration from mesenchymal stromal cells (MSC) is attributed to comprehensive
immune modulation mediated by the MSC. However, the temporal and spatial regulation of …

Mesenchymal stem cells (MSCs) exhibit self-renewal, multi-lineage differentiation potential
and immunomodulatory properties, and are promising candidates for cellular therapy of …

Transforming growth factor beta (TGF-β) is ubiquitously found in bone and plays a key role
in bone turnover. Mice expressing constitutively active TGF-β receptor type I (Mx1; TβRICA …

One of the greatest challenges in improving prostate cancer (PCa) survival is in designing
new therapies to effectively target bone metastases. PCa regulation of the bone environment …

Small Extracellular Vesicles (sEVs) derived from Mesenchymal Stem Cells (MSCs) have
emerged as a promising avenue for cell-free therapeutics in regenerative medicine. These …