Significance: Scarring of the skin from burns, surgery, and injury constitutes a major burden
on the healthcare system. Patients affected by major scars, particularly children, suffer from …

Scar formation is a consequence of the wound healing process that occurs when body
tissues are damaged by a physical injury. Hypertrophic scars and keloids are pathological …

The endogenous electric field (EF) generated by transepithelial potential difference plays a
decisive role in wound reepithelialization. For patients with large or chronic wounds …

This randomized, controlled, within-subjects (crossover design) study examined the effects
of immersive virtual reality as an adjunctive analgesic technique for hospitalized pediatric …

The objective of this study was to compare the effect of virtual reality to passive distraction
and standard care on burn treatment pain in adolescents. This single-blinded, randomized …

Hypertrophic scars, resulting from alterations in the normal processes of cutaneous wound
healing, are characterized by proliferation of dermal tissue with excessive deposition of …

The development of more effective methods of relieving pain associated with burn injury is a
major unmet medical need. Not only is acute burn injury pain a source of immense suffering …

A variety of conservative treatments for burn scars are available, but there is no clear
consensus on the evidence. The purpose of this study was to summarize the available …

Sharar SR, Carrougher GJ, Nakamura D, Hoffman HG, Blough DK, Patterson DR. Factors
influencing the efficacy of virtual reality distraction analgesia during postburn physical …

Burn trauma ranges from the minor burn to the devastating injury, which can impact on all
aspects of a person's life, including their aesthetic appearance, relationships with others …