M Paulikat, GM Piccini, E Ippoliti… - Journal of Chemical …, 2023 - ACS Publications
We provide a molecular-level description of the thermodynamics and mechanistic aspects of drug permeation through the cell membrane. As a case study, we considered the antimalaria …
The global pharma industry is facing new challenges due to generic competition, patent expirations, and lack of innovations. Hence, the adaptation of innovative and cost-effective …
M Kundu, A Dutta, KK Roy, SK Mal… - Chemical Biology & …, 2023 - Wiley Online Library
Malaria continues to be a significant public health problem threatened by the emergence and spread of resistance to artemisinin‐based combination therapies and marked half a …
We provide a molecular-level description of the thermodynamics and mechanistic aspects of drug permeation through the cell membrane. As a case study, we considered the anti …
P Kumar, I Ghosh - Biophysical and Computational Tools in Drug …, 2021 - Springer
Needless to say that cure from malaria disease is a longstanding goal and helping the present worldwide effort to reduce the malarial disease burden by many folds. Chloroquine …
Till today, malaria remains one of the most prominent infectious diseases in the world. Since the beginning of the decade, the number of malaria cases has drastically decreased, in no …
It is a significant challenge to assess the functions of many uncharacterized genes in human malaria parasites. Here, we present a genetic screening tool to assess the contribution of …