For half a century, we have known that some patients experience neurocognitive dysfunction
after cardiac surgery, yet defining its incidence, course, and causes remains challenging …

Cognitive recovery after anaesthesia and surgery is a concern for older adults, their families,
and caregivers. Reports of patients who were 'never the same'prompted a scientific inquiry …

Ever since Bedford's seminal Lancet case series in 1955, we have known that perioperative
care is sometimes followed by significant cognitive dysfunction (1). Although the safety of …

Multicomponent interventions are effective in preventing postoperative delirium, and work is
ongoing to determine if they can be effective in preventing other postoperative …

Cognitive Reserve and the Risk of Postoperative Cognitive Dysfunction - PMC Back to Top
Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage …

Each year over 16 million older Americans undergo general anesthesia for surgery, and up
to 40% develop postoperative delirium and/or cognitive dysfunction (POCD). Delirium and …

As increasing numbers of elderly people undergo cardiac surgery, neurologists are
frequently called upon to assess patients with neurological complications from the …

Objective Numerous investigators have theorized that postoperative changes in Alzheimer's
disease neuropathology may underlie postoperative neurocognitive disorders. Thus, we …

A decline in cognitive function is a frequent complication of major surgery. Postoperative
cognitive impairments have generally been divided into short-(postoperative delirium) and …

Background: Neurofilament light is a marker of neuronal injury and can be measured in
blood. Postoperative increases in neurofilament light have been associated with delirium …