Correlation between in vitro toxicity of pesticides and in vivo risk guidelines in support of complex operating site risk management: A meta-analysis

M Alehashem, S Mamet, N Hogan, M Hecker… - Food and Chemical …, 2022 - Elsevier
In vitro cell systems can support hazard characterization and identify mechanisms involved
in toxicity; however, using in vitro data for risk assessment still is challenging. As part of an …

Evaluate the Toxicity of Pyrethroid Insecticide Cypermethrin before and after Biodegradation by Lysinibacillus cresolivuorans Strain HIS7

E Saied, A Fouda, AM Alemam, MH Sultan… - Plants, 2021 - mdpi.com
Herein, bacterial isolate HIS7 was obtained from contaminated soil and exhibited high
efficacy to degrade pyrethroid insecticide cypermethrin. The HIS7 isolate was identified as …

Cypermethrin induces Sertoli cell apoptosis through mitochondrial pathway associated with calcium

HX Wang, R Zhang, Z Li, LS Wang, Y Yu… - Toxicology …, 2021 - academic.oup.com
Cypermethrin, one kind of pyrethroid pesticides, has been shown to act as endocrine-
disrupting chemicals (EDCs). The purpose of this study was to explore the roles of Sertoli …

Cytomodulatory characteristics of Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) against cypermethrin on skin fibroblast cells (HFF-1)

S Aghajanshakeri, R Ataee, M Karami… - Toxicology, 2023 - Elsevier
The hematopoietic factor granulocyte macrophage-colony stimulating factor (GM-CSF) has
been identified via its capacity to promote bone marrow progenitors' development and …

Platinum nanoparticles induced genotoxicity and apoptotic activity in human normal and cancer hepatic cells via oxidative stress‐mediated Bax/Bcl‐2 and caspase‐3 …

MHA Almarzoug, D Ali, S Alarifi… - Environmental …, 2020 - Wiley Online Library
Platinum nanoparticles (PtNPs) attract much attention due to their excellent biocompatibility
and catalytic properties, but their toxic effects on normal (CHANG) and cancerous (HuH‐7) …

Green platinum nanoparticles interaction with HEK293 cells: Cellular toxicity, apoptosis, and genetic damage

RS Almeer, D Ali, S Alarifi, S Alkahtani… - Dose …, 2018 - journals.sagepub.com
Metal nanoparticles are widely used in industry, agriculture, textiles, drugs, and so on. The
adverse effect of green platinum nanoparticles on human embryonic kidney (HEK293) cells …

Autophagy perturbation upon acute pyrethroid treatment impacts adipogenic commitment of mesenchymal stem cells

J Verma, AK Rai, NK Satija - Pesticide Biochemistry and Physiology, 2023 - Elsevier
Environmental chemical exposure can cause dysregulation in adipogenesis that can result
in metabolic syndrome, which includes insulin resistance, type 2 diabetes, cardiovascular …

[HTML][HTML] The protective effect of Ammi visnaga extract against human hepatic cancer

MW Arafah, B Almutairi, M Al-Zharani… - Journal of King Saud …, 2021 - Elsevier
Cancer is the most serious disease globally and it's the second in mortality rate after heart
failure. Hepatic cancer is a common cancer disease worldwide. This investigation was …

Beta-cypermethrin-induced stress response and ABC transporter-mediated detoxification in Tetrahymena thermophila

W Zhang, W Lei, T Bo, J Xu, W Wang - … and Physiology Part C: Toxicology & …, 2025 - Elsevier
Abstract β-Cypermethrin (β-CYP), a synthetic pyrethroid pesticide, is widely used for insect
management. However, it also affects non-target organisms and pollutes aquatic …

[HTML][HTML] Evaluation of Ramucirumab as a combinational cancer therapeutic with 5-Aza-citidine in human Hepatoma (HuH-7) cell line

H Almasoud, S Alarifi, S Alkahtani - Journal of King Saud University …, 2024 - Elsevier
The purpose of this study is to explore the impact of Ramucirumab alone and combined with
5-Aza on different cellular targets in human hepatocellular carcinoma cell line (HuH-7). Cells …