spirooxindoles are important synthetic target compounds and play special role in organic
chemistry because of their extensive biological activities and applications of pharmaceutical …

This review presents the advances in the use of 6-aminouracil as a starting material in the
synthesis of various heterocyclic structures such as pyrido-, pyrrolo-, and pyrimido …

A new wave of dual Topo I/II inhibitors was designed and synthesised via the hybridisation
of spirooxindoles and pyrimidines. In situ selenium nanoparticles (SeNPs) for some …

An efficient one-pot synthesis of spiro [indoline-3, 4′-pyrano [2, 3-c] pyrazole] derivatives by
four-component reaction of hydrazine, β-keto ester, isatin, and malononitrile or ethyl …

A simple, facile, efficient and three-component procedure for the synthesis of spiro [indoline-
3, 4′-pyrazolo [3, 4-b] pyridine]-2, 6′(1′ H)-diones by the reaction of 4-hydroxycumarin …

5-Formyl-6-aminopyrimidine-2, 4-(1H, 3H)-dione (2) has been previously prepared from
compound 1. Cyclocondensation reaction of compound 2 with cyanoacetamide gave …

A one-pot, pseudo four-component method for the efficient and simple synthesis of spiro
[diindeno [1, 2-b: 2′, 1′-e] pyridine-11, 3′-indoline]-2′, 10, 12-trione derivatives in …

A one-pot, pseudo four-component, and simple synthesis of spiro [diindenopyridine-
indoline] triones and spiro [acenaphthylene-diindenopyridine] triones via the reaction of 1, 3 …

The synthesis of 2-amino-4-cyano-4H-chromene derivatives as new HA 14-1 analogues by
a simple and efficient method is reported. In addition, the reaction of 2-amino-2H-chromene …

A novel and facile one‐pot synthesis of spiro cyclic 2‐oxindole derivatives of pyrimido [4, 5‐
b] quinoline‐4, 6‐dione, pyrido [2, 3‐d: 6, 5‐d′] dipyrimidine‐2, 4, 6‐trione, and indeno …