Purpose: The purpose of this focused review was to explore the etiologies of corneal
blindness worldwide and compare them with the indications and type of keratoplasties (eg …

Corneal dystrophies are broadly defined as inherited disorders that affect any layer of the
cornea and are usually progressive, bilateral conditions that do not have systemic effects …

Effective prophylaxis and treatment of corneal graft rejection are essential to improve
outcomes in corneal transplantation. To date, there has been no standardized protocol …

Macular corneal dystrophy is a corneal stromal dystrophy which leads to progressive vision
loss. Macular corneal dystrophy is an autosomal recessive condition in which there is …

Purpose Endothelial failure and immunological graft rejection remain long-term
complications leading to late graft failure in penetrating keratoplasty (PK). Deep anterior …

Lamellar keratoplasty procedures have gained momentum in the field of corneal
transplantation because of their inherent advantages over full-thickness penetrating …

Purpose: Millions worldwide suffer vision impairment or blindness from corneal injury, and
there remains an urgent need for a more effective and accessible way to treat corneal …

ABSTRACT Macular Corneal Dystrophy is an autosomal recessive form of corneal dystrophy
due to a mutation in CHST6 gene, which results in abnormal proteoglycan synthesis. There …

1. Gomes JA, Tan D, Rapuano CJ, et al. Global consensus on keratoconus and ectatic
diseases. Cornea. 2015; 34: 359-369. 2. Binder PS, Lindstrom RL, Stulting RD, et al …

Corneal dystrophies are a heterogeneous group of bilateral, inherited, rare diseases
characterized by slowly progressive corneal opacities, that lead to visual impairment. Most of …