The impact of maternal diabetes on the future health and neurodevelopment of the offspring: a review of the evidence

K Rodolaki, V Pergialiotis, N Iakovidou… - Frontiers in …, 2023 - frontiersin.org
Maternal health during gestational period is undoubtedly critical in shaping optimal fetal
development and future health of the offspring. Gestational diabetes mellitus is a metabolic …

Mitochondria in early forebrain development: from neurulation to mid-corticogenesis

RM Fame, MK Lehtinen - Frontiers in Cell and Developmental Biology, 2021 - frontiersin.org
Function of the mature central nervous system (CNS) requires a substantial proportion of the
body's energy consumption. During development, the CNS anlage must maintain its …

Effects of a Diabetic Microenvironment on Neurodegeneration: Special Focus on Neurological Cells

V Chavda, D Yadav, S Patel, M Song - Brain sciences, 2024 - mdpi.com
Diabetes is a chronic metabolic condition associated with high levels of blood glucose which
leads to serious damage to the heart, kidney, eyes, and nerves. Elevated blood glucose …

From songbird to humans: The multifaceted roles of FOXP2 in speech and motor learning

R Valle-Bautista, M Olivera-Acevedo… - Neuroscience & …, 2024 - Elsevier
Motor learning involves a complex network of brain structures and is crucial for tasks like
speech. The cerebral cortex, subcortical nuclei, and cerebellum are involved in motor …

Integrated multi-omics analysis reveals the effect of maternal gestational diabetes on fetal mouse hippocampi

S Luo, K Zou, H Zhu, Y Cheng, Y Yan… - Frontiers in Cell and …, 2022 - frontiersin.org
Growing evidence suggests that adverse intrauterine environments could affect the long-
term health of offspring. Recent evidence indicates that gestational diabetes mellitus (GDM) …

[HTML][HTML] Harmful Effects on the Hippocampal Morpho-Histology and on Learning and Memory in the Offspring of Rats with Streptozotocin-Induced Diabetes

M Salazar-García, L Villavicencio-Guzmán… - International Journal of …, 2024 - mdpi.com
Learning alterations in the child population may be linked to gestational diabetes as a
causal factor, though this remains an open and highly controversial question. In that sense, it …

Increased Nuclear FOXP2 Is Related to Reduced Neural Stem Cell Number and Increased Neurogenesis in the Dorsal Telencephalon of Embryos of Diabetic Rats …

DS De la Merced-García, Á Sánchez-Barrera… - Cells, 2023 - mdpi.com
Diabetic rat embryos have increased cortical neurogenesis and neuron maturation, and their
offspring presented altered neuron polarity, lamination, and diminished neuron excitability …

Biophysical and synaptic properties of regular spiking interneurons in hippocampal area CA3 of aged rats

E Griego, EJ Galván - Neurobiology of Aging, 2022 - Elsevier
Neuronal processing from the dentate gyrus to the hippocampus is critical for storage and
recovery of new memory traces. In area CA3, GABAergic interneurons form a strong barrage …

Long-Term Functional and Cytoarchitectonic Effects of the Systemic Administration of the Histamine H1 Receptor Antagonist/Inverse Agonist Chlorpheniramine …

R Valle-Bautista, B Márquez-Valadez… - Frontiers in …, 2022 - frontiersin.org
The transient histaminergic system is among the first neurotransmitter systems to appear
during brain development in the rat mesencephalon/rhombencephalon. Histamine …

[PDF][PDF] In vitro studies on alpha-amylase inhibitory activities of Zanthoxylum armatum of mid-western regions of Nepal

D Dahal, A Subedee, K Khanal… - Amrit Research Journal, 2021 - academia.edu
The alpha-amylase inhibitors are used as a drug to control hyperglycemia in type II diabetes
mellitus. The plant extract is a natural source to minimize toxicity and other side effects. The …