The descending projections from motor cortex share many features with top-down or
backward connections in visual cortex; for example, corticospinal projections originate in …

Considerable progress has been made in developing models of cerebellar function in
sensorimotor control, as well as in identifying key problems that are the focus of current …

Little is known about the organizational and functional connectivity of the corticospinal (CS)
circuits that are essential for voluntary movement. Here, we map the connectivity between …

Contemporary strategies to promote motor recovery following stroke focus on repetitive
voluntary movements. Although successful movement relies on efficient sensorimotor …

Optimal feedback control (OFC) provides a powerful tool to interpret voluntary motor control,
highlighting the importance of sensory feedback in the control and planning of movement …

Mammalian motor behavior is enabled by a hierarchy of interleaved circuit modules
constructed by interneurons in the spinal cord, sensory feedback loops, and bilateral …

The spinal cord integrates and relays somatosensory input, leading to complex motor
responses. Research over the past couple of decades has identified transcription factor …

The precision of skilled movement depends on sensory feedback and its refinement by local
inhibitory microcircuits. One specialized set of spinal GABAergic interneurons forms axo …

The spinal cord contains neural networks that enable regionally distinct motor outputs along
the body axis. Nevertheless, it remains unclear how segment-specific motor computations …

Cerebellar granule cells constitute the majority of neurons in the brain and are the primary
conveyors of sensory and motor-related mossy fiber information to Purkinje cells. The …