Multiple sequence alignment modeling: methods and applications

M Chatzou, C Magis, JM Chang… - Briefings in …, 2016 - academic.oup.com
This review provides an overview on the development of Multiple sequence alignment
(MSA) methods and their main applications. It is focused on progress made over the past …

A review on multiple sequence alignment from the perspective of genetic algorithm

B Chowdhury, G Garai - Genomics, 2017 - Elsevier
Sequence alignment is an active research area in the field of bioinformatics. It is also a
crucial task as it guides many other tasks like phylogenetic analysis, function, and/or …

TCS: a new multiple sequence alignment reliability measure to estimate alignment accuracy and improve phylogenetic tree reconstruction

JM Chang, P Di Tommaso… - Molecular biology and …, 2014 - academic.oup.com
Multiple sequence alignment (MSA) is a key modeling procedure when analyzing biological
sequences. Homology and evolutionary modeling are the most common applications of …

T-Coffee: Tree-based consistency objective function for alignment evaluation

C Magis, JF Taly, G Bussotti, JM Chang… - Multiple Sequence …, 2014 - Springer
T-Coffee, for Tree-based consistency objective function for alignment evaluation, is a
versatile multiple sequence alignment (MSA) method suitable for aligning virtually any type …

Abalign: a comprehensive multiple sequence alignment platform for B-cell receptor immune repertoires

F Zong, C Long, W Hu, S Chen, W Dai… - Nucleic Acids …, 2023 - academic.oup.com
The utilization of high-throughput sequencing (HTS) for B-cell receptor (BCR) immune
repertoire analysis has become widespread in the fields of adaptive immunity and antibody …

Optimizing multiple sequence alignments using a genetic algorithm based on three objectives: structural information, non-gaps percentage and totally conserved …

FM Ortuno, O Valenzuela, F Rojas, H Pomares… - …, 2013 - academic.oup.com
Abstract Motivation: Multiple sequence alignments (MSAs) are widely used approaches in
bioinformatics to carry out other tasks such as structure predictions, biological function …

Who watches the watchmen? An appraisal of benchmarks for multiple sequence alignment

S Iantorno, K Gori, N Goldman, M Gil… - Multiple sequence …, 2014 - Springer
Multiple sequence alignment (MSA) is a fundamental and ubiquitous technique in
bioinformatics used to infer related residues among biological sequences. Thus alignment …

A hybrid multiobjective memetic metaheuristic for multiple sequence alignment

Á Rubio-Largo, MA Vega-Rodríguez… - IEEE Transactions …, 2015 - ieeexplore.ieee.org
Over the last 25 years, the multiple sequence alignment (MSA) problem has attracted the
attention of biologists because it is one of the major techniques used in several areas of …

Evaluating statistical multiple sequence alignment in comparison to other alignment methods on protein data sets

M Nute, E Saleh, T Warnow - Systematic biology, 2019 - academic.oup.com
The estimation of multiple sequence alignments of protein sequences is a basic step in
many bioinformatics pipelines, including protein structure prediction, protein family …

Comparing multi-objective metaheuristics for solving a three-objective formulation of multiple sequence alignment

C Zambrano-Vega, AJ Nebro, J García-Nieto… - Progress in Artificial …, 2017 - Springer
Multiple sequence alignment (MSA) is an optimization problem consisting in finding the best
alignment of more than two biological sequences according to a number of scores or …