COVID-19 for the cardiologist: basic virology, epidemiology, cardiac manifestations, and potential therapeutic strategies
Summary Coronavirus disease-2019 (COVID-19), a contagious disease caused by severe
acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), has reached pandemic status. As …
acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), has reached pandemic status. As …
[HTML][HTML] Insights into antiviral mechanisms of remdesivir, lopinavir/ritonavir and chloroquine/hydroxychloroquine affecting the new SARS-CoV-2
K Uzunova, E Filipova, V Pavlova, T Vekov - Biomedicine & …, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) is a kind of viral pneumonia with an unusual
outbreak in Wuhan, China, which is caused by severe acute respiratory syndrome …
outbreak in Wuhan, China, which is caused by severe acute respiratory syndrome …
Targeting endosomal acidification by chloroquine analogs as a promising strategy for the treatment of emerging viral diseases
MAA Al‐Bari - Pharmacology research & perspectives, 2017 - Wiley Online Library
Emerging viruses such as HIV, dengue, influenza A, SARS coronavirus, Ebola, and other
viruses pose a significant threat to human health. Majority of these viruses are responsible …
viruses pose a significant threat to human health. Majority of these viruses are responsible …
Effects of chloroquine on viral infections: an old drug against today's diseases
A Savarino, JR Boelaert, A Cassone… - The Lancet infectious …, 2003 - thelancet.com
Chloroquine is a 9-aminoquinoline known since 1934. Apart from its well-known antimalarial
effects, the drug has interesting biochemical properties that might be applied against some …
effects, the drug has interesting biochemical properties that might be applied against some …
COVID-19 for the cardiologist: a current review of the virology, clinical epidemiology, cardiac and other clinical manifestations and potential therapeutic strategies
The coronavirus disease-2019 (COVID-19), a contagious disease caused by severe acute
respiratory syndrome coronavirus-2 (SARS-CoV2), has reached pandemic status. As it …
respiratory syndrome coronavirus-2 (SARS-CoV2), has reached pandemic status. As it …
A systematic screen of FDA-approved drugs for inhibitors of biological threat agents
Background The rapid development of effective medical countermeasures against potential
biological threat agents is vital. Repurposing existing drugs that may have unanticipated …
biological threat agents is vital. Repurposing existing drugs that may have unanticipated …
Chloroquine for influenza prevention: a randomised, double-blind, placebo controlled trial
Background Chloroquine has in-vitro activity against influenza and could be an ideal
candidate for worldwide prevention of influenza in the period between onset of a pandemic …
candidate for worldwide prevention of influenza in the period between onset of a pandemic …
[HTML][HTML] The burden of co-infection with human immunodeficiency virus type 1 and malaria in pregnant women in sub-saharan Africa
FO Ter Kuile, ME Parise, FH Verhoeff… - … Intolerable Burden of …, 2004 - ncbi.nlm.nih.gov
In sub-Saharan Africa, human immunodeficiency virus (HIV) and malaria are among the
leading causes of morbidity during pregnancy. We reviewed available information collected …
leading causes of morbidity during pregnancy. We reviewed available information collected …
Effects of hydroxychloroquine on immune activation and disease progression among HIV-infected patients not receiving antiretroviral therapy: a randomized controlled …
NI Paton, RL Goodall, DT Dunn, S Franzen… - Jama, 2012 - jamanetwork.com
Context Therapies to decrease immune activation might be of benefit in slowing HIV disease
progression. Objective To determine whether hydroxychloroquine decreases immune …
progression. Objective To determine whether hydroxychloroquine decreases immune …
Hydroxychloroquine drastically reduces immune activation in HIV-infected, antiretroviral therapy–treated immunologic nonresponders
S Piconi, S Parisotto, G Rizzardini… - Blood, The Journal …, 2011 - ashpublications.org
Despite optimal suppression of HIV replication, restoration of CD4+ T cells is not always
achieved in antiretroviral therapy–treated individuals. Defective CD4 recovery in …
achieved in antiretroviral therapy–treated individuals. Defective CD4 recovery in …