Alkaline phosphatase (ALP) is an enzyme that catalyzes the dephosphorylation of various
vital nucleic acids and proteins. A broad range of physiological and pathological processes …

Determination of specific cardiac biomarkers (CBs) during the diagnosis and management
of adverse cardiovascular events such as acute myocardial infarction (AMI) has become …

Diethanolamine (DEA) has been extensively utilized as an alkaline buffer in current assays
of alkaline phosphatase (ALP) activity in the past decades. While playing the role of a buffer …

Indium tin oxide (ITO), as an electrode, has superiority over metal electrodes commonly
used for electroanalysis due to its low cost, low electrochemical background response, wide …

Advanced nanomaterials have attracted ever-growing interest in design and construction of
electrochemical immunosensors, which hold great promise to improve sensitivity in …

A functional electrochemical immunosensor was successfully designed for simultaneous
and high sensitivity detection of carcinoembryonic antigen (CEA) and α-fetoprotein (AFP) …

Electrochemical–electrochemical (EE) redox cycling using interdigitated array (IDA)
electrodes is a simple and efficient approach for signal amplification. However, IDA …

Amide hydrolysis using enzyme labels, such as proteases, occurs at a slower rate than
phosphoester and carboxyl ester hydrolysis. Thus, it is not very useful for obtaining high …

Biomolecule-conjugated metal nanoparticles (NPs) have been primarily used as colorimetric
labels in affinity-based bioassays for point-of-care testing. A facile electrochemical detection …

This study involves the fabrication of a sandwich-type electrochemical immunosensor for
sensitive and simultaneous detection of alpha-fetoprotein (AFP) and cancer embryo antigen …