Lactase persistence—the ability of adults to digest the lactose in milk—varies widely in
frequency across human populations. This trait represents an adaptation to the …

Genetic information contains a record of the history of our species, and technological
advances have transformed our ability to access this record. Many studies have used …

Southern Africa is consistently placed as a potential region for the evolution of Homo
sapiens. We present genome sequences, up to 13x coverage, from seven ancient …

Despite broad agreement that Homo sapiens originated in Africa, considerable uncertainty
surrounds specific models of divergence and migration across the continent. Progress is …

Some of humanity's earliest ancestors lived in southern Africa and evidence from sites there
has inspired key debates on human origins and the emergence of complex cognition …

In humans the ability to digest milk lactose is conferred by a β-galactosidase enzyme called
lactase-phlorizin hydrolase (LPH). While in some humans (approximately two-thirds of …

Abstract The southern African indigenous Khoe-San populations harbor the most divergent
lineages of all living peoples. Exploring their genomes is key to understanding deep human …

Africa hosts the greatest human genetic diversity globally, but legacies of ancient population
interactions and dispersals across the continent remain understudied. Here, we report …

Abstract South Eastern Bantu-speaking (SEB) groups constitute more than 80% of the
population in South Africa. Despite clear linguistic and geographic diversity, the genetic …

Similarity between two individuals in the combination of genetic markers along their
chromosomes indicates shared ancestry and can be used to identify historical connections …