Upon resolution of an acute viral infection, during latent‐reactivating infection and during
chronic active infections virus‐specific T‐cells differentiate into distinct subsets that differ in …

Abstract CD4 and CD8 T cells are key players in the immune response against both
pathogenic infections and cancer. CD4 T cells provide help to CD8 T cells via multiple …

Abstract Chronic Epstein-Barr virus (EBV) infection after pediatric organ transplantation (Tx)
accounts for significant morbidity and mortality. The risk of complications, such as …

The spleen is a conserved secondary lymphoid organ that emerged in parallel to adaptive
immunity in early jawed vertebrates. Recent studies have applied single cell transcriptomics …

Gut microbes exhibit complex interactions with their hosts and shape an organism's immune
system throughout its lifespan. As the largest secondary lymphoid organ, the spleen has a …

Over the past 15 years, single-cell RNA sequencing (scRNA-seq) technology, in
combination with other omics, has revealed the mechanisms of human development …

Although lymph node structures may be compromised in severe SARS-CoV-2 infection, the
extent and parameters of recovery in convalescing patients remain unclear. Therefore, this …

Breast cancer is commonly thought of as a “women's disease”. However, men are
increasingly diagnosed with the disease, and their mortality rates are disparately higher than …

BK Polyomavirus is of particular concern for kidney transplant recipients, due to their
immunosuppression. This problem is exacerbated by the high effectiveness of antirejection …

Purpose: To determine the effect of combining oseltamivir, artificial cow-bezoar,
chlorphenamine maleate, and interferon inhalation on immune function and serum amyloid …