Oncolytic viruses (OVs) have attracted growing awareness in the twenty-first century, as they
are generally considered to have direct oncolysis and cancer immune effects. With the …

Despite advances in treatment, cancer remains a leading cause of death worldwide.
Although treatment strategies are continually progressing, cancers have evolved many …

Simple Summary The cancer-immunity cycle is characterized by various stimulatory and
inhibitory factors, which together regulate the immune response and halt the extreme …

Over the last 60 years an eclectic collection of microbes has been tested in a variety of pre-
clinical models as anti-cancer agents. At the forefront of this research are a number of virus …

Vesicular stomatitis virus (VSV), a negative-strand RNA virus of the Vesiculovirus genus, has
demonstrated encouraging anti-neoplastic activity across multiple human cancer types. VSV …

Oncolytic viruses represent an exciting new aspect of the evolving field of cancer
immunotherapy. We have engineered a novel hybrid vector comprising vesicular stomatitis …

Oncolytic virus (OV) is a replication competent virus that selectively invades cancer cells; as
these cells die under the viral burden, the released virus particles proceed to infect other …

Vaccines of outstanding efficiency, safety, and public acceptance are needed to halt the
current SARS-CoV-2 pandemic. Concerns include potential side effects caused by the …

Oncolytic viruses have attracted attention as a promising strategy in cancer therapy owing to
their ability to selectively infect and kill tumor cells, without affecting healthy cells. They also …

The reovirus fusion-associated small transmembrane (FAST) proteins are the smallest
known viral fusogens (∼ 100–150 amino acids) and efficiently induce cell-cell fusion and …