In human pathophysiology, the clash between microbial infection and host immunity
contributes to multiple diseases. Cystic fibrosis (CF) is a classical example of this …

Chemotherapy is a cornerstone of cancer treatment, but it can also induce immune
suppression, which can have significant implications for patient outcomes. This review paper …

Pseudomonas aeruginosa (PA) CbpD belongs to the lytic polysaccharide monooxygenases
(LPMOs), a family of enzymes that cleave chitin or related polysaccharides. Here, we …

The release of neutrophil extracellular traps (NETs), either during “suicidal” or “vital”
NETosis, represents an important strategy of neutrophils to combat Gram-negative bacteria …

Lung infections caused by the opportunistic pathogen Pseudomonas aeruginosa can
present as a spectrum of clinical entities from a rapidly fatal pneumonia in a neutropenic …

One of the hallmarks of opportunistic pathogens is their ability to adjust and respond to a
wide range of environmental and host-associated conditions. The human pathogen …

Innate immune responses play a critical role in controlling acute infections due to
Pseudomonas aeruginosa in both mice and in humans. In this review we focus on innate …

Pf bacteriophage are temperate phages that infect the bacterium Pseudomonas aeruginosa,
a major cause of chronic lung infections in cystic fibrosis (CF) and other settings. Pf and …

Pseudomonas aeruginosa is an opportunistic bacterial pathogen responsible for a high
incidence of acute and chronic pulmonary infection. These infections are particularly …

Abstract Aims: Pulmonary infections with Pseudomonas aeruginosa are a serious clinical
problem and are often lethal. Because many strains of P. aeruginosa are resistant to …