Prostate cancer (PCa), known as a heterogenous disease, has a high incidence and
mortality rate around the world and seriously threatens public health. As an inevitable by …

Glutathione peroxidases (GPxs) belong to a family of enzymes that is important in
organisms; these enzymes promote hydrogen peroxide metabolism and protect cell …

Background C. vespertiliomis extracts were evaluated for antiproliferative and apoptosis
effect on breast cancer (MCF7) cells. Methods and results The leaves extracts were …

Chemo-resistant cancer cells acquire robust growth potential through cell signaling
mechanisms such as the down-regulation of tumor suppressors and the up-regulation of pro …

Clinacanthus nutans dichloromethane fraction (CN-Dcm) extract has previously been
proven to suppress breast cancer (MCF7) cell proliferation. Despite this, the extrinsic and …

Breast cancer (BC) is the most frequently diagnosed cancer with a low survival rate and one
of the major causes of cancer-related death. Methotrexate (MTX) is an anti-tumor drug used …

Mammary tumors affect intact and elderly female dogs, and almost 50% of these cases are
malignant. Cell culture offers a promising preclinical model to study this disease and creates …

Twenty new quinazolinone derivatives bearing a piperonyl moiety were designed and
synthesized. The structures of the target compounds were in agreement with the …

Aim ZCJ14, a gefitinib analog, exhibited prominent anti-cancer effect both in vitro and in
vivo. The present study aims to investigate the inhibitory effects of ZCJ14 on human cancer …

A pair of undescribed enantiomers,(±) ficusflavonid A (1a/1b), along with five known
analogues, were isolated from the roots of Ficus hirta. Their structures were determined by …