Objective Stem cells are considered to be one of the greatest potential treatments to cure
degenerative diseases. Stem cells injection for knee osteoarthritis is still a relatively new …

Adipose tissue stem cells (ASCs), known as multipotent stem cells, are most commonly used
in the clinical applications in recent years. Adipose tissues (AT) have the advantage in the …

In patients with Crohn's disease, perianal fistulas recur frequently, causing substantial
morbidity. We performed a 12-patient, 6-month, phase 1 trial to determine whether …

The prevalence of osteoarthritis (OA), a degenerative disorder of joints, has substantially
increased in recent years. Its key pathogenic hallmarks include articular cartilage …

Adipose tissue contains adult mesenchymal stem cells that may modulate the metabolism
when applied to other tissues. Stromal vascular fraction (SVF) can be isolated from adipose …

Aim To provide a systematic analysis of the study design in knee osteoarthritis (OA)
preclinical studies, focusing on the characteristics of animal models and cell doses, and to …

Ezh2 is a histone methyltransferase that suppresses osteoblast maturation and skeletal
development. We evaluated the role of Ezh2 in chondrocyte lineage differentiation and …

Osteoarthritis (OA) is an inflammatory joint disease that affects cartilage, subchondral bone,
and joint tissues. Undifferentiated Mesenchymal Stromal Cells are a promising therapeutic …

Osteoarthritis (OA) is a debilitating disease affecting approximately 27 million Americans. 1
The most common symptoms of OA are pain and physical limitations that have a significant …

Chemotherapy can cause ovarian dysfunction and infertility since the ovary is extremely
sensitive to chemotherapeutic drugs. Apart from the indispensable role of the ovary in the …