Gestational diabetes mellitus: a harbinger of the vicious cycle of diabetes
EU Alejandro, TP Mamerto, G Chung… - International journal of …, 2020 - mdpi.com
Gestational diabetes mellitus (GDM), characterized by a transitory form of diabetes induced
by insulin resistance and pancreatic β-cell dysfunction during pregnancy, has been …
by insulin resistance and pancreatic β-cell dysfunction during pregnancy, has been …
Maternal obesity during pregnancy and cardiovascular development and disease in the offspring
R Gaillard - European journal of epidemiology, 2015 - Springer
Maternal obesity during pregnancy is an important public health problem in Western
countries. Currently, obesity prevalence rates in pregnant women are estimated to be as …
countries. Currently, obesity prevalence rates in pregnant women are estimated to be as …
Maternal obesity, diabetes during pregnancy and epigenetic mechanisms that influence the developmental origins of cardiometabolic disease in the offspring
P Agarwal, TS Morriseau, SM Kereliuk… - Critical reviews in …, 2018 - Taylor & Francis
Since 1980, global obesity has doubled, and the incidence of cardiometabolic diseases
such as type 2 diabetes and heart disease is also increasing. While genetic susceptibility …
such as type 2 diabetes and heart disease is also increasing. While genetic susceptibility …
Association between artificially sweetened beverage consumption during pregnancy and infant body mass index
MB Azad, AK Sharma, RJ de Souza… - JAMA …, 2016 - jamanetwork.com
Importance The consumption of artificial sweeteners has increased substantially in recent
decades, including among pregnant women. Animal studies suggest that exposure to …
decades, including among pregnant women. Animal studies suggest that exposure to …
Maternal consumption of artificially sweetened beverages during pregnancy is associated with infant gut microbiota and metabolic modifications and increased infant …
I Laforest-Lapointe, AB Becker, PJ Mandhane… - Gut …, 2021 - Taylor & Francis
Artificial sweetener consumption by pregnant women has been associated with an
increased risk of infant obesity, but the underlying mechanisms are unknown. We aimed to …
increased risk of infant obesity, but the underlying mechanisms are unknown. We aimed to …
The link between gestational diabetes and cardiovascular diseases: potential role of extracellular vesicles
Extracellular vesicles are critical mediators of cell communication. They encapsulate a
variety of molecular cargo such as proteins, lipids, and nucleic acids including miRNAs …
variety of molecular cargo such as proteins, lipids, and nucleic acids including miRNAs …
Exposure to gestational diabetes mellitus induces neuroinflammation, derangement of hippocampal neurons, and cognitive changes in rat offspring
B Vuong, G Odero, S Rozbacher, M Stevenson… - Journal of …, 2017 - Springer
Background Birth cohort studies link gestational diabetes mellitus (GDM) with impaired
cognitive performance in the offspring. However, the mechanisms involved are unknown …
cognitive performance in the offspring. However, the mechanisms involved are unknown …
Maternal obesity characterized by gestational diabetes increases the susceptibility of rat offspring to hepatic steatosis via a disrupted liver metabolome
TJ Pereira, MA Fonseca, KE Campbell… - The Journal of …, 2015 - Wiley Online Library
Key points Gestational diabetes mellitus is a common complication of pregnancy, but its
effects on the offspring are poorly understood. We developed a rat model of diet‐induced …
effects on the offspring are poorly understood. We developed a rat model of diet‐induced …
Early-life exposure to non-nutritive sweeteners and the developmental origins of childhood obesity: global evidence from human and rodent studies
AJ Archibald, VW Dolinsky, MB Azad - Nutrients, 2018 - mdpi.com
Non-nutritive sweeteners (NNS) are increasingly consumed by children and pregnant
women around the world, yet their long-term health impact is unclear. Here, we review an …
women around the world, yet their long-term health impact is unclear. Here, we review an …
[HTML][HTML] Maternal high-fat high-sucrose diet and gestational exercise modulate hepatic fat accumulation and liver mitochondrial respiratory capacity in mothers and …
J Stevanović-Silva, J Beleza, P Coxito, S Pereira… - Metabolism, 2021 - Elsevier
Background Maternal high-caloric nutrition and related gestational diabetes mellitus (GDM)
are associated with a high-risk for developing metabolic complications later in life and in …
are associated with a high-risk for developing metabolic complications later in life and in …