The human major histocompatibility complex is a family of genes that encodes HLAs, which
have a crucial role in defence against foreign pathogens and immune surveillance of …

Due to the ongoing shortage of deceased-donor organs, novel strategies to augment kidney
transplantation rates through expanded living donation strategies have become essential …

HLA (Human Leucocyte Antigen) sensitization is a significant barrier to successful kidney
transplantation. It often translates into difficult crossmatch before transplant and increased …

Results The simulation indicated that 2111 of 10,988 kidneys (19.2%) would have been
allocated to patients with cPRA 100% versus 74 of 10,988 (0.7%) that were actually …

Solid phase immunoassays (SPI) are now routinely used to detect HLA antibodies.
However, the flow cytometric crossmatch (FCXM) remains the established method for …

Background. It is estimated that 19.2% of kidneys exported for candidates with> 98%
calculated panel reactive antibodies are transplanted into unintended recipients, most …

Esta guía de recomendaciones para el TR de donante vivo (TRDV) es un documento
elaborado con el patrocinio de la Sociedad Española de Nefrología, la Sociedad Española …

Detection and characterization of HLA antibodies with solid phase immunoassays has led to
increased understanding of the role of those antibodies in graft rejection, improved treatment …

Introduction: Highly sensitized patients awaiting a kidney transplant accrue on the transplant
waiting list. The breadth of HLA antibodies in this subpopulation of patients precludes …

With organs in short supply, only a limited number of kidney transplants can be performed a
year. Live donor donation accounts for 1/3rd of all kidney transplants performed in the …