Nanovehicles can efficiently carry and deliver anticancer agents to tumour sites. Compared
with normal tissue, the tumour microenvironment has some unique properties, such as …

The tumor microenvironment (TME) is a complex and dynamic entity, comprising stromal
cells, immune cells, blood vessels and extracellular matrix, which is intimately associated …

Matrix metalloproteinases (MMPs) are a class of endopeptidases that are dependent on zinc
and facilitate the degradation of extracellular matrix (ECM) proteins, thereby playing pivotal …

Optical techniques used in medical diagnosis, surgery, and therapy require efficient and
flexible delivery of light from light sources to target tissues. While this need is currently …

Simple Summary Despite access to a vast arsenal of anticancer agents, many fail to realise
their full therapeutic potential in clinical practice. One key determinant of this is the evolution …

Drug delivery has made tremendous advances in the last decade. Targeted therapies are
increasingly common, with intracellular delivery highly impactful and sought after …

Background. Matrix metalloproteinase‐9 (MMP‐9) can degrade the extracellular matrix and
participate in tumor progression. The relationship between MMP‐9 and immune cells has …

The tumor microenvironment is the cellular environment that is also described as the “soil”
for supporting tumor growth, proliferation, invasion and metastasis, as well as protecting …

Proteases are considered of major importance in biomedical research because of their
crucial roles in health and disease. Their ability to hydrolyze their protein and peptide …

Matrix metalloproteinases (MMPs) have long been implicated for roles in cancer initiation,
tumor growth, and metastasis. However, pancreatic cancer clinical trials using broad-based …