Parkin paves the path to antitumor immunity: Expanding Parkin's role as a tumor suppressor

H Kim, AR Ze'ev - The Journal of Clinical Investigation, 2024 - jci.org
Parkin, a ring-between-ring-type E3 ubiquitin ligase, first shown to play a critical role in
autosomal recessive juvenile Parkinsonism, has recently emerged as a key player in cancer …

Detoxification of Chlorfenapyr by a Parkin-GSTd2 Module in Bactrocera dorsalis (Diptera: Tephritidae)

C Xie, B Zeng, X Du, S Yan, J Shen… - Journal of Agricultural …, 2024 - ACS Publications
The oriental fruit fly, Bactrocera dorsalis (Hendel), is a highly invasive and destructive pest.
Chlorfenapyr is a widely used insecticide that disrupts mitochondrial activity. The Parkin …

[HTML][HTML] Parkin modulates the hepatocellular carcinoma microenvironment by regulating PD-1/PD-L1 signalling

G Ye, X Sun, J Li, M Pu, J Zhang - Journal of Advanced Research, 2025 - Elsevier
Introduction Parkin-mediated mitophagy is essential for the clearance of damaged
mitochondria, and it inhibits tumour development. The role of mitophagy in modulating …