Photo-cross-linking to delineate epigenetic interactome
Covalent modifications of DNA and histones are key cellular epigenetic marks to regulate
gene functions. Most of these epigenetic marks are added or removed by corresponding …
gene functions. Most of these epigenetic marks are added or removed by corresponding …
Molecular insights into the recognition of acetylated histone modifications by the BRPF2 bromodomain
HBO1 [HAT bound to the origin recognition complex (ORC)], a member of the MYST family of
histone acetyltransferases (HATs), was initially identified as a binding partner of ORC that …
histone acetyltransferases (HATs), was initially identified as a binding partner of ORC that …
Uncovering the non-histone interactome of the BRPF1 bromodomain using site-specific azide-acetyllysine photochemistry
Bromodomain-PHD finger protein 1 (BRPF1) belongs to the BRPF family of bromodomain-
containing proteins. Bromodomains are exclusive reader modules that recognize and bind …
containing proteins. Bromodomains are exclusive reader modules that recognize and bind …
Novel insights into the recognition of acetylated histone H4 tail by the TRIM24 PHD-Bromo module
TRIM24 is a multi-functional chromatin reader, and it binds to the estrogen receptor to
activate estrogen-dependent target genes associated with tumor development. TRIM24 is …
activate estrogen-dependent target genes associated with tumor development. TRIM24 is …