Acquisition of cell fate is thought to rely on the specific interaction of remote cis-regulatory
modules (CRMs), for example, enhancers and target promoters. However, the precise …

Abstract Schizophrenia's (SZ's) heritability and familial transmission have been known for
several decades; however, despite the clear evidence for a genetic component, it has been …

Toll signaling plays a crucial role in pathogen defense throughout the animal kingdom. It
was discovered, however, for its function in dorsoventral (DV) axis formation in Drosophila …

The capacity of the honey bee to produce three phenotypically distinct organisms (two
female castes; queens and sterile workers, and haploid male drones) from one genotype …

Morphogen gradients specify cell fates during development, with a classic example being
the bone morphogenetic protein (BMP) gradient's conserved role in embryonic dorsal …

In the developmental remodeling of brain circuits, neurons are removed by glial
phagocytosis to optimize adult behavior. Fragile X mental retardation protein (FMRP) …

Bone Morphogenetic Protein (BMP) patterns the dorsal–ventral (DV) embryonic axis in all
vertebrates, but it is unknown how cells along the DV axis interpret and translate the …

Regulation of mRNA degradation is critical for a diverse array of cellular processes and
developmental cell fate decisions. Many methods for determining mRNA half-lives rely on …

The honey bee genome has the capacity to produce three phenotypically distinct organisms
(two diploid female castes: queen and worker, and a haploid male drone). Previous studies …

In the mid-1960s, bone morphogenetic proteins (BMPs) were first identified in the extracts of
bone to have the remarkable ability to induce heterotopic bone. When the Drosophila gene …