Neuroinflammation in bipolar depression

F Benedetti, V Aggio, ML Pratesi, G Greco… - Frontiers in …, 2020 - frontiersin.org
Bipolar disorder (BD) is a leading cause of worldwide disability among mood disorders.
Pathological mechanisms are still vastly unclear, and current treatments with conventional …

Biological hypotheses and biomarkers of bipolar disorder

E Sigitova, Z Fišar, J Hroudová… - Psychiatry and …, 2017 - Wiley Online Library
The most common mood disorders are major depressive disorders and bipolar disorders
(BD). The pathophysiology of BD is complex, multifactorial, and not fully understood …

Cytokine alterations in bipolar disorder: a meta-analysis of 30 studies

A Modabbernia, S Taslimi, E Brietzke, M Ashrafi - Biological psychiatry, 2013 - Elsevier
BACKGROUND: We conducted a meta-analysis of studies comparing cytokine
concentrations between patients with bipolar disorder (BD) and healthy control subjects …

Integrated neurobiology of bipolar disorder

V Maletic, C Raison - Frontiers in psychiatry, 2014 - frontiersin.org
From a neurobiological perspective there is no such thing as bipolar disorder. Rather, it is
almost certainly the case that many somewhat similar, but subtly different, pathological …

Anti‐inflammatory agents in the treatment of bipolar depression: a systematic review and meta‐analysis

JD Rosenblat, R Kakar, M Berk, LV Kessing… - Bipolar …, 2016 - Wiley Online Library
Objective Inflammation has been implicated in the risk, pathophysiology, and progression of
mood disorders and, as such, has become a target of interest in the treatment of bipolar …

[HTML][HTML] Sex differences in the blood–brain barrier: implications for mental health

L Dion-Albert, LB Binder, B Daigle, A Hong-Minh… - Frontiers in …, 2022 - Elsevier
Prevalence of mental disorders, including major depressive disorder (MDD), bipolar
disorder (BD) and schizophrenia (SZ) are increasing at alarming rates in our societies …

Chemokines and chemokine receptors in mood disorders, schizophrenia, and cognitive impairment: a systematic review of biomarker studies

MJ Stuart, BT Baune - Neuroscience & Biobehavioral Reviews, 2014 - Elsevier
The search for immune biomarkers in psychiatric disorders has primarily focused on pro-
inflammatory cytokines. Other immune proteins including chemokines have been relatively …

A systematic review of evidence for the role of inflammatory biomarkers in bipolar patients

P Sayana, GD Colpo, LR Simoes, VV Giridharan… - Journal of psychiatric …, 2017 - Elsevier
Bipolar disorder (BD) is a neuropsychiatric disorder that is characterized by a phasic course
of affective episodes interspersed with a euthymic state. Epidemiological, clinical, genetic …

Bipolar disorder and inflammation

JD Rosenblat, RS McIntyre - Psychiatric Clinics, 2016 - psych.theclinics.com
Methods For this narrative clinical overview, the MEDLINE/PubMed, Embase, Google
Scholar and ClinicalTrials. gov databases were searched from inception through June 2015 …

A peripheral inflammatory signature discriminates bipolar from unipolar depression: a machine learning approach

S Poletti, B Vai, MG Mazza, R Zanardi, C Lorenzi… - Progress in Neuro …, 2021 - Elsevier
Background Mood disorders (major depressive disorder, MDD, and bipolar disorder, BD)
are considered leading causes of life-long disability worldwide, where high rates of no …