Disturbed flow (d-flow) induces atherosclerosis by regulating gene expression in endothelial
cells (ECs). For further mechanistic understanding, we carried out a single-cell RNA …

Cardiovascular complications are associated with advanced atherosclerosis. Although
atherosclerosis is still regarded as an incurable disease, at least in its more advanced …

Cancer metastasis and secondary tumor initiation largely depend on circulating tumor cell
(CTC) and vascular endothelial cell (EC) interactions by incompletely understood …

Arterial endothelial function is acutely and chronically regulated by blood flow-associated
shear stress. An acute intervention employing modest forearm cuff occlusion to …

Acutely imposed oscillatory shear stress (OSS) reduces reactive hyperemia flow-mediated
dilation (RH-FMD) in conduit arteries of men; however, whether a similar impairment occurs …

The increase of blood pressure accelerates endothelial progenitor cells (EPCs) senescence,
hence a significant reduction in the number of EPCs is common in patients with …

Background Mental stress (MS) is related to endothelial dysfunction in overweight/obese
men. It is believed that the pro-oxidant profile, associated with an imbalance in the vascular …

The main goal was to determine the impact of mental stress (MS) on blood flow regulation in
overweight/obese men. Fourteen overweight/obese men (27±7 years; 29.8±2.6 kg/m2) …

Objective: The inability of the organism to appropriately respond to hypoxia results in
abnormal cell metabolism and function. Hypoxia-induced angiogenesis seems to be …

Introduction Disturbed blood flow, characterized by high retrograde and oscillatory shear
rate (SR), is associated with a proatherogenic phenotype. The impact of disturbed blood flow …