The older adult brain is less modular, more integrated, and less efficient at rest: A systematic review of large‐scale resting‐state functional brain networks in aging

HA Deery, R Di Paolo, C Moran, GF Egan… - …, 2023 - Wiley Online Library
The literature on large‐scale resting‐state functional brain networks across the adult
lifespan was systematically reviewed. Studies published between 1986 and July 2021 were …

Separating vascular and neuronal effects of age on fMRI BOLD signals

KA Tsvetanov, RNA Henson… - … Transactions of the …, 2021 - royalsocietypublishing.org
Accurate identification of brain function is necessary to understand the neurobiology of
cognitive ageing, and thereby promote well-being across the lifespan. A common tool used …

Functional brain networks reflect spatial and temporal autocorrelation

M Shinn, A Hu, L Turner, S Noble, KH Preller, JL Ji… - Nature …, 2023 - nature.com
High-throughput experimental methods in neuroscience have led to an explosion of
techniques for measuring complex interactions and multi-dimensional patterns. However …

Extending the Human Connectome Project across ages: Imaging protocols for the Lifespan Development and Aging projects

MP Harms, LH Somerville, BM Ances, J Andersson… - Neuroimage, 2018 - Elsevier
Abstract The Human Connectome Projects in Development (HCP-D) and Aging (HCP-A) are
two large-scale brain imaging studies that will extend the recently completed HCP Young …

Global signal regression strengthens association between resting-state functional connectivity and behavior

J Li, R Kong, R Liégeois, C Orban, Y Tan, N Sun… - NeuroImage, 2019 - Elsevier
Global signal regression (GSR) is one of the most debated preprocessing strategies for
resting-state functional MRI. GSR effectively removes global artifacts driven by motion and …

Influence of sample size and analytic approach on stability and interpretation of brain‐behavior correlations in task‐related fMRI data

CL Grady, JR Rieck, D Nichol… - Human Brain …, 2021 - Wiley Online Library
Limited statistical power due to small sample sizes is a problem in fMRI research. Most of the
work to date has examined the impact of sample size on task‐related activation, with less …

The effect of aging on resting state connectivity of predefined networks in the brain

E Varangis, CG Habeck, QR Razlighi… - Frontiers in aging …, 2019 - frontiersin.org
Recent studies have found a deleterious effect of age on a wide variety of measures of
functional connectivity, and some hints at a relationship between connectivity at rest and …

Local structure-function relationships in human brain networks across the lifespan

F Zamani Esfahlani, J Faskowitz, J Slack… - Nature …, 2022 - nature.com
A growing number of studies have used stylized network models of communication to predict
brain function from structure. Most have focused on a small set of models applied globally …

[HTML][HTML] Dispersion of functional gradients across the adult lifespan

RAI Bethlehem, C Paquola, J Seidlitz, L Ronan… - Neuroimage, 2020 - Elsevier
Ageing is commonly associated with changes to segregation and integration of functional
brain networks, but, in isolation, current network-based approaches struggle to elucidate …

Segregation of functional networks is associated with cognitive resilience in Alzheimer's disease

M Ewers, Y Luan, L Frontzkowski, J Neitzel, A Rubinski… - Brain, 2021 - academic.oup.com
Cognitive resilience is an important modulating factor of cognitive decline in Alzheimer's
disease, but the functional brain mechanisms that support cognitive resilience remain …