Current concepts, opportunities, and challenges of gut microbiome-based personalized medicine in nonalcoholic fatty liver disease

SR Sharpton, B Schnabl, R Knight, R Loomba - Cell metabolism, 2021 - cell.com
Nonalcoholic fatty liver disease (NALFD) is now a leading cause of chronic liver disease
worldwide, in part, as a consequence of rapidly rising levels of obesity and metabolic …

[HTML][HTML] Role of nutrition in the pathogenesis and prevention of non-alcoholic fatty liver disease: recent updates

R Ullah, N Rauf, G Nabi, H Ullah, Y Shen… - … journal of biological …, 2019 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease (NAFLD) is an acquired metabolic disease characterized by
triglycerides (TGs) deposition in liver induced by other factors rather than alcohol …

Machine learning identifies ferroptosis-related gene ANXA2 as potential diagnostic biomarkers for NAFLD

J Qin, P Cao, X Ding, Z Zeng, L Deng… - Frontiers in …, 2023 - frontiersin.org
Introduction Non-alcoholic fatty liver disease (NAFLD), a major cause of chronic liver
disease, still lacks effective therapeutic targets today. Ferroptosis, a type of cell death …

[HTML][HTML] The contribution of sterile inflammation to the fatty liver disease and the potential therapies

ME Shaker - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Hepatic inflammation is prevalent in several metabolic liver diseases. Recent scientific
advances about the pathogenesis of metabolic liver diseases showed an emerging role of …

Phytocannabinoids Reduce Inflammation of Primed Macrophages and Enteric Glial Cells: An In Vitro Study

G Cohen, O Gover, B Schwartz - International Journal of Molecular …, 2023 - mdpi.com
Intestinal inflammation is mediated by a subset of cells populating the intestine, such as
enteric glial cells (EGC) and macrophages. Different studies indicate that phytocannabinoids …

Efferocytosis in multisystem diseases

Y Zhang, Y Wang, J Ding, P Liu - Molecular medicine …, 2022 - spandidos-publications.com
Efferocytosis, the phagocytosis of apoptotic cells performed by both specialized phagocytes
(such as macrophages) and non‑specialized phagocytes (such as epithelial cells), is …

Hepatoprotective effects of Methyl ferulic acid on alcohol-induced liver oxidative injury in mice by inhibiting the NOX4/ROS-MAPK pathway

C Li, L Li, C Yang, Y Zhong, D Wu, L Shi… - … and biophysical research …, 2017 - Elsevier
Aims The present study aimed to investigate the hepatoprotective effects of Methyl ferulic
acid (MFA) against oxidative stress and apoptosis as well as inflammation in mice with liver …

Oxymatrine alleviated hepatic lipid metabolism via regulating miR-182 in non-alcoholic fatty liver disease

H Zhang, L Yang, Y Wang, W Huang, Y Li, S Chen… - Life Sciences, 2020 - Elsevier
Aims This study aimed to investigate oxymatrine via regulating miR-182 improved the
hepatic lipid accumulation in non-alcoholic fatty liver disease (NAFLD) model. Materials and …

Early microcystin-LR exposure-linked inflammasome activation in mice causes development of fatty liver disease and insulin resistance

M Al-Badrani, P Saha, A Mondal, RK Seth… - Environmental …, 2020 - Elsevier
Evidence from pediatric studies show that infants and children are at risk for early exposure
to microcystin. The present report tests the hypothesis that early life exposure to microcystin …

Sparstolonin B exerts beneficial effects on prostate cancer by acting on the reactive oxygen species‐mediated PI3K/AKT pathway

S Liu, J Hu, C Shi, L Sun, W Yan… - Journal of Cellular and …, 2021 - Wiley Online Library
Prostate cancer is a major health concern in males worldwide, owing to its high incidence.
Sparstolonin B (SsnB), a component of the Chinese herbal medicine Sparganium …