Publisher Summary This chapter focuses on recent biochemical and biophysical studies that
examine the nucleic acid chaperone function of HIV‐1 nucleocapsid protein (NC) and its …

Retrovirus particles contain a small, basic protein, the nucleocapsid (NC) protein, that
possessesnucleic acid chaperone'activity-that is, the NC protein can catalyze the …

A number of abundant mobile genetic elements called retrotransposons reverse transcribe
RNA to generate DNA for insertion into eukaryotic genomes. Four major classes of …

The genetic diversity of human immunodeficiency virus type 1 (HIV-1) results from a
combination of point mutations and genetic recombination, and rates of both processes are …

Abstract Since the Human Immunodeficiency Virus Type 1 (HIV‐1) was identified as the
etiologic agent of the Acquired Immune Deficiency Syndrome (AIDS), the HIV‐1 reverse …

One salient feature of reverse transcription in retroviruses, notably in the human
immunodeficiency virus type 1, is that it requires the homologous nucleocapsid (NC) protein …

Human immunodeficiency virus type 1 (HIV-1) and other retroviruses replicate through
reverse transcription, a process in which the single stranded RNA of the viral genome is …

The nucleocapsid protein (NC) of human immunodeficiency virus type 1 (HIV-1) has two zinc
fingers, each containing the invariant metal ion binding residues CCHC. Recent reports …

The role of nucleocapsid protein (NC) in the early steps of retroviral replication appears
largely that of a facilitator for reverse transcription and integration. Using a wide variety of …

RNA chaperones are ubiquitous and abundant proteins found in all living organisms and
viruses, where they interact with various classes of RNA. These highly diverse families of …