Bloodstream infections (BSIs) are common in hospitals, often life-threatening and increasing
in prevalence. Microorganisms in the blood are usually rapidly cleared by the immune …

Neutrophils are critical in the host defense against Staphylococcus aureus, a major human
pathogen. However, even in the setting of a robust neutrophil response, S. aureus can …

Advances in technology and software have radically expanded the scope of metabolomics
studies and allow us to monitor a broad transect of central carbon metabolism in routine …

Type VI secretion systems (T6SS), recently described in hypervirulent K. pneumoniae (hvKp)
strains, are involved in bacterial warfare but their role in classical clinical strains (cKp) has …

Gram-negative bacteremia is a major cause of global morbidity involving three phases of
pathogenesis: initial site infection, dissemination, and survival in the blood and filtering …

Bacteria communicate with their surroundings through diverse secretory systems, and the
recently discovered Type VI Secretion System (T6SS) has gained significant attention …

Klebsiella pneumoniae (Kp) infection is an important healthcare concern. The ST258
classical (c) Kp strain is dominant in hospital-acquired infections in North America and …

Background: Staphylococcus aureus (S. aureus) is a common cause of hospital-and
community-acquired infections that can result in various clinical manifestations ranging from …

Melatonin has various physiological effects, such as the maintenance of circadian rhythms,
anti-inflammatory functions, and regulation of intestinal barriers. The regulatory functions of …

Background The gut microbiota is a complex microbial community that changes in response
to various intestinal diseases, including aging-related diseases such as sarcopenia. Several …