[HTML][HTML] Prenatal psychological or metabolic stress increases the risk for psychiatric disorders: the “funnel effect” model

C Musillo, A Berry, F Cirulli - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
Adverse stressful experiences in utero can redirect fetal brain development, ultimately
leading to increased risk for psychiatric disorders. Obesity during pregnancy can have …

[HTML][HTML] Postpartum depression: Aetiology, pathogenesis and the role of nutrients and dietary supplements in prevention and management

GP Rupanagunta, M Nandave, D Rawat… - Saudi Pharmaceutical …, 2023 - Elsevier
Postpartum depression (PPD) is a challenging psychological disorder faced by 10–30% of
mothers across the globe. In India, it occurs among 22% of mothers. Its aetiology and …

Prenatal maternal stress is associated with site-specific and age acceleration changes in maternal and newborn DNA methylation

EB Quinn, CJ Hsiao, FM Maisha, CJ Mulligan - Epigenetics, 2023 - Taylor & Francis
Prenatal maternal stress has a negative impact on child health but the mechanisms through
which maternal stress affects child health are unclear. Epigenetic variation, such as DNA …

Epigenome-wide association studies of prenatal maternal mental health and infant epigenetic profiles: a systematic review

E Drzymalla, KS Crider, A Wang, G Marta… - Translational …, 2023 - nature.com
Prenatal stress and poor maternal mental health are associated with adverse offspring
outcomes; however, the biological mechanisms are unknown. Epigenetic modification has …

Maternal attachment insecurity, maltreatment history, and depressive symptoms are associated with broad DNA methylation signatures in infants

TK Robakis, MC Roth, LS King, KL Humphreys… - Molecular …, 2022 - nature.com
The early environment, including maternal characteristics, provides many cues to young
organisms that shape their long-term physical and mental health. Identifying the earliest …

Attitudes toward seeking professional psychological help among Chinese pregnant women: a cross-sectional study

S Huang, M Xiao, Y Hu, G Tang, Z Chen… - Journal of Affective …, 2023 - Elsevier
Background There exists a gap between the high prevalence of mental health problems and
negative attitudes toward seeking professional psychological help among Chinese pregnant …

Leukocyte methylomic imprints of exposure to the genocide against the Tutsi in Rwanda: a pilot epigenome-wide analysis

C Musanabaganwa, AH Wani, J Donglasan… - …, 2022 - Taylor & Francis
Aim & methods: We conducted a pilot epigenome-wide association study of women from
Tutsi ethnicity exposed to the genocide while pregnant and their resulting offspring, and a …

Stress during pregnancy and epigenetic modifications to offspring DNA: a systematic review of associations and implications for preterm birth

AL Nowak, CM Anderson, AR Mackos… - The Journal of …, 2020 - journals.lww.com
Offspring born preterm (ie, before 37 weeks of gestation) are more likely to die or experience
long-standing illness than full-term offspring. Maternal genetic variants (ie, heritable, stable …

Epigenetic mechanisms in the neurodevelopmental theory of depression

M Talarowska - Depression research and treatment, 2020 - Wiley Online Library
The genome (genes), epigenome, and environment work together from the earliest stages of
human life to produce a phenotype of human health or disease. Epigenetic modifications …

Maternal prenatal lead levels and neonatal brain volumes: Testing moderations by maternal depressive symptoms and family income

AC Wylie, SJ Short, RC Fry, WR Mills-Koonce… - Neurotoxicology and …, 2024 - Elsevier
There is considerable evidence that prenatal lead exposure is detrimental to child cognitive
and socio-emotional development. Further evidence suggests that the effects of prenatal …