Identifying biases and their potential solutions in human microbiome studies

JT Nearing, AM Comeau, MGI Langille - Microbiome, 2021 - Springer
Advances in DNA sequencing technology have vastly improved the ability of researchers to
explore the microbial inhabitants of the human body. Unfortunately, while these studies have …

Gut microbiome in multiple sclerosis: the players involved and the roles they play

SK Shahi, SN Freedman, AK Mangalam - Gut microbes, 2017 - Taylor & Francis
The human gut contains trillions of bacteria (microbiome) that play a major role in
maintaining a healthy state for the host. Perturbation of this healthy gut microbiome might be …

Contrasting the relative importance of species sorting and dispersal limitation in shaping marine bacterial versus protist communities

W Wu, HP Lu, A Sastri, YC Yeh, GC Gong… - The ISME …, 2018 - academic.oup.com
A central challenge in microbial ecology is to understand the underlying mechanisms driving
community assembly, particularly in the continuum of species sorting and dispersal …

Response of soil properties and microbial communities to agriculture: Implications for primary productivity and soil health indicators

P Trivedi, M Delgado-Baquerizo, IC Anderson… - Frontiers in Plant …, 2016 - frontiersin.org
Agricultural intensification is placing tremendous pressure on the soil's capacity to maintain
its functions leading to large-scale ecosystem degradation and loss of productivity in the …

Back to basics–the influence of DNA extraction and primer choice on phylogenetic analysis of activated sludge communities

M Albertsen, SM Karst, AS Ziegler, RH Kirkegaard… - PloS one, 2015 - journals.plos.org
DNA extraction and primer choice have a large effect on the observed community structure
in all microbial amplicon sequencing analyses. Although the biases are well known, no …

Determining the most accurate 16S rRNA hypervariable region for taxonomic identification from respiratory samples

R López-Aladid, L Fernández-Barat… - Scientific reports, 2023 - nature.com
Abstract 16S rRNA gene profiling, which contains nine hypervariable regions (V1–V9), is the
gold standard for identifying taxonomic units by high-throughput sequencing. Microbiome …

Identification of universal gut microbial biomarkers of common human intestinal diseases by meta-analysis

L Mancabelli, C Milani, GA Lugli… - FEMS microbiology …, 2017 - academic.oup.com
Intestinal diseases, such as Crohn's disease (CD), ulcerative colitis (UC) and
pseudomembranous colitis (CDI), are among the most common diseases in humans and …

Hemolymph microbiome of Pacific oysters in response to temperature, temperature stress and infection

A Lokmer, KM Wegner - The ISME journal, 2015 - academic.oup.com
Microbiota provide their hosts with a range of beneficial services, including defense from
external pathogens. However, host-associated microbial communities themselves can act as …

Characterization of Intestinal Bacteria in Wild and Domesticated Adult Black Tiger Shrimp (Penaeus monodon)

W Rungrassamee, A Klanchui, S Maibunkaew… - PloS one, 2014 - journals.plos.org
The black tiger shrimp (Penaeus monodon) is a marine crustacean of economic importance
in the world market. To ensure sustainability of the shrimp industry, production capacity and …

Carbon content and climate variability drive global soil bacterial diversity patterns

M Delgado‐Baquerizo, FT Maestre… - Ecological …, 2016 - Wiley Online Library
Despite the vital role of microorganisms for ecosystem functioning and human welfare, our
understanding of their global diversity and biogeographical patterns lags significantly …