Several haematological malignancies, including multiple myeloma (MM) and acute myeloid
leukaemia (AML), have well-defined precursor states that precede the development of overt …

As one of the most abundant immune cell populations in the tumor microenvironment (TME),
tumor‐associated macrophages (TAMs) play important roles in multiple solid malignancies …

Immune profiling in patients with monoclonal gammopathy of undetermined significance
(MGUS), smoldering multiple myeloma (SMM), and multiple myeloma (MM) provides the …

Multiple myeloma (MM) is a malignant disease of plasma cells with complex pathology,
causing significant morbidity due to its end-organ destruction. The outcomes of patients with …

Multiple myeloma (MM) is a hematological malignancy characterized by clonal proliferation
of plasma cells. Although therapeutic advances have been made to improve clinical …

Arginine methyltransferases critically regulate cellular homeostasis by modulating the
functional outcome of their substrates. The protein arginine methyltransferase 5 (PRMT5) is …

Multiple Myeloma (MM) is the second most common hematological malignancy after non-
Hodgkin lymphoma and is manifested by uncontrolled proliferation and accumulation of …

Obesity and obesogenic behaviors are positively associated with both monoclonal
gammopathy of unknown significance (MGUS) and multiple myeloma (MM). As the only …

Natural Killer (NK) cells act as important regulators in the development and progression of
hematological malignancies and their suppressor activity against Multiple Myeloma (MM) …

Tumor microenvironments are rich in extracellular nucleotides that can be metabolized by
ectoenzymes to produce adenosine, a nucleoside involved in controlling immune …