This brief review provides a practical guide for drug combination studies and delineates its
essence in terms of the mass-action-based theory, experimental design and automated …

This brief perspective article focuses on the most common errors and pitfalls, as well as the
do's and don'ts in drug combination studies, in terms of experimental design, data …

Poly (ADP-ribose) polymerase inhibitors (PARPis) are clinically effective predominantly for
BRCA-mutant tumors. We introduce a mechanism-based strategy to enhance PARPi efficacy …

Efficient and cancer cell-targeted delivery of photosensitizer (PS) and therapeutic protein
has great potentiality for improving the anticancer effects. Herein, zeolitic imidazolate …

Diallyl disulfide (DADS) is an oil-soluble organosulfur compound found in garlic. The effect
of synthetic DADS on the growth of estrogen receptor (ER)-positive (KPL-1 and MCF-7) and …

Although gastrointestinal stromal tumors (GISTs) harboring activating KIT or platelet-derived
growth factor receptor A (PDGFRA) mutations respond to treatment with targeted …

Fidelity of chromosome segregation is ensured by a tension‐dependent error correction
system that prevents stabilization of incorrect chromosome–microtubule attachments …

An in vitro model for oral cancer was used to examine the growth inhibitory effects of
chemopreventive agents when used singly and in combination. The model consists of …

Exploiting vulnerabilities in the intracellular signaling pathways of tumor cells is a key
strategy for the development of new drugs. The activation of cellular stress responses …

Recent X-ray crystallographic determination of the HIV-1 envelope glycoprotein gp41 core
structure opened up a new avenue to discover antiviral agents for chemotherapy of HIV-1 …