Obesity is a global health difficulty characterized by an excessive accumulation of fat that
increases body weight. Obesity has been studied in multiple animal models, of which those …

In recent decades, traditional eating habits have been replaced by a more globalized diet,
rich in saturated fatty acids and simple sugars. Extensive evidence shows that these dietary …

Human genome-wide association studies (GWAS) suggest a functional role for central
glutamate receptor signaling and plasticity in body weight regulation. Here, we use UK …

A link between obesity and cerebral health is receiving growing recognition. Here, we
investigate in the frontal cortex and hippocampus the potential involvement of cholinergic …

The progression of metabolic diseases, featured by dysregulated metabolic signaling
pathways, is orchestrated by numerous signaling networks. Among the regulators, ion …

Background: Considering that health behaviors and personality traits play an important role
in the formation of health attitudes, the main objective of this study was to evaluate the …

Oxidative stress and inflammation induced by abundant consumption of high-energy foods
and caloric overload are implicated in the dysfunction of the blood‒brain barrier (BBB) …

Simple Summary Obesity is a well-known condition responsible for being a risk factor for
cardiovascular disease progression. The intake of bioactive phytochemicals, contained in …

Metabolic imbalance contributes to cognitive impairment, anxiety, depressive behavior, and
impaired olfactory perception. Recent studies have focused on olfactory dysfunction in …

It is well known that the G protein-gated inwardly rectifying K+(GIRK) channels are critical to
maintain excitability of central neurons. GIRK channels consist of 4 subunits and …