The immunopeptidome is the repertoire of peptides bound and presented by the MHC class
I, class II, and non-classical molecules. The peptides are produced by the degradation of …

Abstract Ribosome profiling (Ribo-Seq) has proven transformative for our understanding of
the human genome and proteome by illuminating thousands of noncanonical sites of …

Abstract The SysteMHC Atlas v1. 0 was the first public repository dedicated to mass
spectrometry-based immunopeptidomics. Here we introduce a newly released version of the …

Peptidomics is the comprehensive characterization of peptides from biological sources
instead of heading for a few single peptides in former peptide research. Mass spectrometry …

Targeted synthetic vaccines have the potential to transform our response to viral outbreaks,
yet the design of these vaccines requires a comprehensive knowledge of viral immunogens …

Simple Summary The major histocompatibility complex class II-associated peptide
proteomics assay is widely used during preclinical immunogenicity risk assessments to …

Comprehensive and in-depth identification of the human leukocyte antigen class I (HLA-I)
and class II (HLA-II) tumor immunopeptidome can inform the development of cancer …

The identification of immunogenic peptides has become essential in an increasing number
of fields in immunology, ranging from tumor immunotherapy to vaccine development. The …

Intercellular communication is fundamental to multicellular life and a core determinant of
outcomes during viral infection, where the common goals of virus and host for persistence …

Throughout history, the influenza A virus has caused numerous devastating global
pandemics. Macrophages, as pivotal innate immune cells, exhibit a wide range of immune …