[HTML][HTML] Fundamental developments in infrared spectroscopic imaging for biomedical applications

M Pilling, P Gardner - Chemical Society reviews, 2016 - pubs.rsc.org
Infrared chemical imaging is a rapidly emerging field with new advances in instrumentation,
data acquisition and data analysis. These developments have had significant impact in …

Application of vibrational spectroscopy and imaging to point-of-care medicine: A review

S Pahlow, K Weber, J Popp, BR Wood… - Applied …, 2018 - journals.sagepub.com
Vibrational spectroscopy and imaging promise molecular information that can be rapidly
acquired without the need for specialized stains or dyes, thereby potentially simplifying and …

Infrared spectroscopic imaging advances as an analytical technology for biomedical sciences

TP Wrobel, R Bhargava - Analytical chemistry, 2018 - ACS Publications
Optical chemical imaging seeks to nondestructively acquire spatially resolved chemical
information without the use of labels or probes. The combination of vibrational mid-infrared …

[HTML][HTML] Spectroscopic imaging of biomaterials and biological systems with FTIR microscopy or with quantum cascade lasers

JA Kimber, SG Kazarian - Analytical and bioanalytical chemistry, 2017 - Springer
Spectroscopic imaging of biomaterials and biological systems has received increased
interest within the last decade because of its potential to aid in the detection of disease using …

Massive datasets and machine learning for computational biomedicine: trends and challenges

A Kocheturov, PM Pardalos, A Karakitsiou - Annals of Operations …, 2019 - Springer
This survey paper attempts to cover a broad range of topics related to computational
biomedicine. The field has been attracting great attention due to a number of benefits it can …

Vibrational spectroscopy as a tool for studying drug-cell interaction: Could high throughput vibrational spectroscopic screening improve drug development?

LE Jamieson, HJ Byrne - Vibrational Spectroscopy, 2017 - Elsevier
Vibrational spectroscopy is currently widely explored as a tool in biomedical applications. An
area at the forefront of this field is the use of vibrational spectroscopy for disease diagnosis …

Single-cell analysis using Fourier transform infrared microspectroscopy

J Doherty, G Cinque, P Gardner - Applied Spectroscopy Reviews, 2017 - Taylor & Francis
Fourier transform infrared spectroscopy (FTIR) is a well-established, non-destructive method
of obtaining chemical information from biological samples such as tissues and cells. This …

[HTML][HTML] Can mid-infrared biomedical spectroscopy of cells, fluids and tissue aid improvements in cancer survival? A patient paradigm

C Hughes, MJ Baker - Analyst, 2016 - pubs.rsc.org
This review will take a fresh approach from the patient perspective; offering insight into the
applications of mid-infrared biomedical spectroscopy in a scenario whereby the patient …

Label-free imaging of lipid-rich biological tissues by mid-infrared photoacoustic microscopy

Y He, J Shi, MA Pleitez, K Maslov… - Journal of …, 2020 - spiedigitallibrary.org
Significance: Mid-infrared (IR) imaging based on the vibrational transition of biomolecules
provides good chemical-specific contrast in label-free imaging of biology tissues, making it a …

Raman and infrared spectroscopy distinguishing replicative senescent from proliferating primary human fibroblast cells by detecting spectral differences mainly due to …

K Eberhardt, C Beleites, S Marthandan… - Analytical …, 2017 - ACS Publications
Cellular senescence is a terminal cell cycle arrested state, assumed to be involved in tumor
suppression. We studied four human fibroblast cell strains (BJ, MRC-5, IMR-90, and WI-38) …