[HTML][HTML] Pathophysiologic relationship between Alzheimer's disease, cerebrovascular disease, and cardiovascular risk: a review and synthesis

CY Santos, PJ Snyder, WC Wu, M Zhang… - Alzheimer's & Dementia …, 2017 - Elsevier
As the population ages due to demographic trends and gains in life expectancy, the
incidence and prevalence of dementia increases, and the need to understand the etiology …

A major role for cardiovascular burden in age-related cognitive decline

C Qiu, L Fratiglioni - Nature Reviews Cardiology, 2015 - nature.com
The incidence of dementia and cardiovascular disease (CVD) increases with age. Current
evidence supports the role for both atherosclerosis and arteriosclerosis as a common …

Associations between cardiovascular risk, structural brain changes, and cognitive decline

R Song, H Xu, CS Dintica, KY Pan, X Qi… - Journal of the American …, 2020 - jacc.org
Background The impact of cardiovascular risk burden on cognitive trajectories and brain
structure changes remains unclear. Objectives This study aimed to examine whether …

Heart disease as a risk factor for dementia

BN Justin, M Turek, AM Hakim - Clinical epidemiology, 2013 - Taylor & Francis
As life expectancy lengthens, dementia is becoming a significant human condition in terms
of its prevalence and cost to society worldwide. It is important in that context to understand …

Sex-specific effects of microglial activation on Alzheimer's disease proteinopathy in older adults

KB Casaletto, E Nichols, V Aslanyan, SM Simone… - Brain, 2022 - academic.oup.com
Females show a disproportionate burden of Alzheimer's disease pathology and higher
Alzheimer's disease dementia prevalences compared to males, yet the mechanisms driving …

Cardiovascular disease risk models and longitudinal changes in cognition: a systematic review

SL Harrison, J Ding, EYH Tang, M Siervo, L Robinson… - PloS one, 2014 - journals.plos.org
Background Cardiovascular disease and its risk factors have consistently been associated
with poor cognitive function and incident dementia. Whether cardiovascular disease …

Roles of brain angiotensin II in cognitive function and dementia

M Mogi, J Iwanami, M Horiuchi - International Journal of …, 2012 - Wiley Online Library
The brain renin‐angiotensin system (RAS) has been highlighted as having a pathological
role in stroke, dementia, and neurodegenerative disease. Particularly, in dementia …

Cardiovascular risk score, cognitive decline, and dementia in older M exican A mericans: the role of sex and education

AZA Hazzouri, MN Haan, JM Neuhaus… - Journal of the …, 2013 - Am Heart Assoc
Background The purpose of this study was to examine the associations of cardiovascular
disease (CVD) risk with cognitive decline and incidence of dementia and cognitive …

Smoking is associated with impaired verbal learning and memory performance in women more than men

CR Lewis, JS Talboom, MD De Both, AM Schmidt… - Scientific reports, 2021 - nature.com
Vascular contributions to cognitive impairment and dementia (VCID) include structural and
functional blood vessel injuries linked to poor neurocognitive outcomes. Smoking might …

The effect of midlife cardiovascular risk factors on white matter hyperintensity volume and cognition two decades later in normal ageing women

R Aljondi, C Szoeke, C Steward, A Gorelik… - Brain imaging and …, 2020 - Springer
Abstract Cerebral White Matter Hyperintensity (WMH) lesions have been identified as
markers of cerebrovascular diseases and they are associated with increased risk of …