Osteosarcoma

HC Beird, SS Bielack, AM Flanagan, J Gill… - Nature reviews Disease …, 2022 - nature.com
Osteosarcoma is the most common primary malignant tumour of the bone. Osteosarcoma
incidence is bimodal, peaking at 18 and 60 years of age, and is slightly more common in …

Current advance of nanotechnology in diagnosis and treatment for malignant tumors

B Wang, S Hu, Y Teng, J Chen, H Wang, Y Xu… - … and Targeted Therapy, 2024 - nature.com
Cancer remains a significant risk to human health. Nanomedicine is a new multidisciplinary
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …

[HTML][HTML] Soft tissue and visceral sarcomas: ESMO–EURACAN–GENTURIS Clinical Practice Guidelines for diagnosis, treatment and follow-up☆

A Gronchi, AB Miah, AP Dei Tos, N Abecassis… - Annals of …, 2021 - Elsevier
Highlights•This Clinical Practice Guideline provides key recommendations on the
management of soft tissue and visceral sarcomas.•Recommendations have been agreed …

UK guidelines for the management of bone sarcomas

C Gerrand, F Amary, HA Anwar, B Brennan… - British Journal of …, 2024 - nature.com
This document is an update of the British Sarcoma Group guidelines (2016) and provides a
reference standard for the clinical care of UK patients with primary malignant bone tumours …

Small round cell sarcomas

F Cidre-Aranaz, S Watson, JF Amatruda… - Nature Reviews …, 2022 - nature.com
Undifferentiated small round cell sarcomas (SRCSs) of bone and soft tissue comprise a
heterogeneous group of highly aggressive tumours associated with a poor prognosis …

Osteosarcoma: current concepts and evolutions in management principles

P Pilavaki, A Gahanbani Ardakani, P Gikas… - Journal of Clinical …, 2023 - mdpi.com
Osteosarcoma is a rare malignancy arising from mesenchymal tissue, and represents the
most common bone sarcoma. The management of osteosarcoma is challenging, and …

[HTML][HTML] Immunotherapy in soft tissue and bone sarcoma: unraveling the barriers to effectiveness

M Panagi, P Pilavaki, A Constantinidou… - Theranostics, 2022 - ncbi.nlm.nih.gov
Sarcomas are uncommon malignancies of mesenchymal origin that can arise throughout the
human lifespan, at any part of the body. Surgery remains the optimal treatment modality …

Deciphering the signaling mechanisms of osteosarcoma tumorigenesis

BK Nirala, T Yamamichi, JT Yustein - International Journal of Molecular …, 2023 - mdpi.com
Osteosarcoma (OS) is the predominant primary bone tumor in the pediatric and adolescent
populations. It has high metastatic potential, with the lungs being the most common site of …

Exosomes in the tumor microenvironment of sarcoma: from biological functions to clinical applications

H Ye, X Hu, Y Wen, C Tu, F Hornicek, Z Duan… - Journal of …, 2022 - Springer
The current diagnosis and treatment of sarcoma continue to show limited timeliness and
efficacy. In order to enable the early detection and management of sarcoma, increasing …

Chondrosarcoma resistance to radiation therapy: Origins and potential therapeutic solutions

A Gilbert, M Tudor, J Montanari, K Commenchail… - Cancers, 2023 - mdpi.com
Simple Summary This review article aims in describing the origins of chondrosarcoma
radiation-resistance and proposes several potential solutions in order to improve the …