The continual supply of ATP to the fundamental cellular processes that underpin skeletal
muscle contraction during exercise is essential for sports performance in events lasting …

Since the lipid profile is altered by physical activity, the study of lipid metabolism is a
remarkable element in understanding if and how physical activity affects the health of both …

Aggressive and metastatic cancers show enhanced metabolic plasticity, but the precise
underlying mechanisms of this remain unclear. Here we show how two NOP2/Sun RNA …

Fat and carbohydrate are important fuels for aerobic exercise and there can be reciprocal
shifts in the proportions of carbohydrate and fat that are oxidized. The interaction between …

Skeletal muscle plays an important role in regulating whole-body energy expenditure given
it is a major site for glucose and lipid oxidation. Obesity and type 2 diabetes are causally …

This review summarizes how fatty acid (FA) oxidation is regulated in skeletal muscle during
exercise. From the available evidence it seems that acetyl-CoA availability in the …

Aims: Impaired fatty acid oxidation (FAO) in mitochondria of hepatocytes causes lipid
accumulation and excessive production of reactive oxygen species (ROS) and oxidative …

Increases in muscle energy needs activate AMPK and induce sarcolemmal recruitment of
the fatty acid (FA) translocase CD36. The resulting rises in FA uptake and FA oxidation are …

The peroxisome proliferator-activated receptors, PPARα, PPARβ, and PPARγ, are a family of
transcription factors activated by a diversity of molecules including fatty acids and fatty acid …

During exercise, the supply of adenosine triphosphate (ATP) is essential for the energy-
dependent processes that underpin ongoing contractile activity. These pathways involve …