Natural products: evidence for neuroprotection to be exploited in glaucoma

A Adornetto, L Rombolà, LA Morrone, C Nucci… - Nutrients, 2020 - mdpi.com
Glaucoma, a leading cause of irreversible blindness worldwide, is an optic neuropathy
characterized by the progressive death of retinal ganglion cells (RGCs). Elevated intraocular …

Evaluation of presumptive biomarkers of oxidative stress, immune response and apoptosis in primary open-angle glaucoma

MD Pinazo-Durán, V Zanón-Moreno… - Current opinion in …, 2013 - Elsevier
There is growing interest on the correlation among oxidative stress, inflammation, apoptosis
and primary open-angle glaucoma initiation and progression. Reactive oxygen species are …

Metabolomic profiling of aqueous humor in glaucoma points to taurine and spermine deficiency: findings from the eye-D study

A Buisset, P Gohier, S Leruez, J Muller… - Journal of proteome …, 2019 - ACS Publications
We compared the metabolomic profile of aqueous humor from patients with primary open-
angle glaucoma (POAG; n= 26) with that of a group of age-and sex-matched non-POAG …

Metabolomics in primary open angle glaucoma: A systematic review and meta-analysis

Y Tang, S Shah, KS Cho, X Sun, DF Chen - Frontiers in Neuroscience, 2022 - frontiersin.org
Glaucoma is a leading cause of blindness worldwide. It is suggested that primary open
angle glaucoma (POAG), the most common form of glaucoma, may be associated with …

[HTML][HTML] The aqueous humor proteome of primary open angle glaucoma: an extensive review

WHG Hubens, RJC Mohren, I Liesenborghs… - Experimental Eye …, 2020 - Elsevier
Background We reviewed the literature on the aqueous humor (AH) proteome of primary
open angle glaucoma (POAG) patients in order to obtain deeper insight into the …

Molecular biomarkers in primary open-angle glaucoma: from noninvasive to invasive

L Agnifili, D Pieragostino, A Mastropasqua… - Progress in brain …, 2015 - Elsevier
Glaucoma, the first cause of irreversible blindness worldwide, is a neurodegenerative
disease characterized by the progressive loss of retinal ganglion cells. There are different …

Monitoring neurodegeneration in glaucoma: therapeutic implications

N Ban, CJ Siegfried, RS Apte - Trends in molecular medicine, 2018 - cell.com
Glaucoma is one of the leading causes of blindness globally, and is characterized by loss of
retinal ganglion cells (RGCs). Because vision loss in glaucoma is not reversible, therapeutic …

Association of dietary intake of B vitamins with glaucoma

J Hou, Y Wen, S Gao, Z Jiang, L Tao - Scientific Reports, 2024 - nature.com
This cross-sectional study investigated the association between glaucoma and B vitamin
dietary intake. A total of 5025 enrolled individuals participated in self-reported glaucoma …

Comparative phospholipid profiles of control and glaucomatous human trabecular meshwork

K Aribindi, Y Guerra, RK Lee… - … & visual science, 2013 - iovs.arvojournals.org
Purpose.: We compared phospholipid (phosphatidylcholine, phosphatidylserine,
phosphatidylethanolamine, and phosphatidylinositol) profiles of control and glaucomatous …

Homocysteine induces oxidative stress to damage trabecular meshwork cells

ZP You, YZ Zhang, YL Zhang… - Experimental and …, 2018 - spandidos-publications.com
The aim of the present study was to investigate the effect of homocysteine (Hcy) in on human
trabecular meshwork cells (HTMCs). A total of 41 patients with primary open‑angle …