[HTML][HTML] Highly cooperative chimeric super-SOX induces naive pluripotency across species
CM MacCarthy, G Wu, V Malik, Y Menuchin-Lasowski… - Cell Stem Cell, 2024 - cell.com
Our understanding of pluripotency remains limited: iPSC generation has only been
established for a few model species, pluripotent stem cell lines exhibit inconsistent …
established for a few model species, pluripotent stem cell lines exhibit inconsistent …
[HTML][HTML] Next-generation direct reprogramming
R Keshri, D Detraux, A Phal, C McCurdy… - Frontiers in Cell and …, 2024 - frontiersin.org
Tissue repair is significantly compromised in the aging human body resulting in critical
disease conditions (such as myocardial infarction or Alzheimer's disease) and imposing a …
disease conditions (such as myocardial infarction or Alzheimer's disease) and imposing a …
Dux activates metabolism-lactylation-MET network during early iPSC reprogramming with Brg1 as the histone lactylation reader
X Hu, X Huang, Y Yang, Y Sun, Y Zhao… - Nucleic acids …, 2024 - academic.oup.com
The process of induced pluripotent stem cells (iPSCs) reprogramming involves several
crucial events, including the mesenchymal-epithelial transition (MET), activation of …
crucial events, including the mesenchymal-epithelial transition (MET), activation of …
Deciphering the Molecular Landscape of the FAM72 Gene Family: Implications for Stem Cell Biology and Cancer
J Ramesh, RM Gopalakrishnan, THA Nguyen… - Neurochemistry …, 2024 - Elsevier
Family with sequence similarity 72 (FAM72) is a protein-coding gene family located on
chromosome 1 in humans, uniquely featuring four paralogs: FAM72A, FAM72B, FAM72C …
chromosome 1 in humans, uniquely featuring four paralogs: FAM72A, FAM72B, FAM72C …
A youthful touch: Reversal of aging hallmarks by cell reprogramming
E Miliotou, I de Lázaro - Cells, Tissues, Organs, 2024 - karger.com
Background: With the elderly population projected to double by 2050, there is an urgent
need to address the increasing prevalence of age-related debilitating diseases and …
need to address the increasing prevalence of age-related debilitating diseases and …
[HTML][HTML] Advancements in personalized stem cell models for aging-related neurodegenerative disorders
Neurodegenerative diseases (NDDs) are a class of disorders characterized by the gradual
loss or malfunction of specific cell populations in the nervous system, which can be triggered …
loss or malfunction of specific cell populations in the nervous system, which can be triggered …
衰老相关神经退行性疾病的个性化干细胞模型研究进展
Neurodegenerative diseases (NDDs) are a class of disorders characterized by the gradual
loss or malfunction of specific cell populations in the nervous system, which can be triggered …
loss or malfunction of specific cell populations in the nervous system, which can be triggered …
後天的なエピゲノムを介した老化制御と世界の動向
早野元詞 - 日本老年医学会雑誌, 2024 - jstage.jst.go.jp
抄録 エピゲノムは, 外的環境やストレスに応じて適切に遺伝子のオンとオフを制御する機能を持って
いる. 近年, DNA メチル化やヒストン修飾, クロマチンリモデリングなどによるエピゲノムは …
いる. 近年, DNA メチル化やヒストン修飾, クロマチンリモデリングなどによるエピゲノムは …