The high prevalence of obesity is associated with an enormous medical, social, and
economic burden. The metabolic dysfunction, dyslipidaemia, and inflammation caused by …

In the last decade, much attention has been devoted to the effects of nutrient-related signals
on brain development and cognitive functions. A turning point was the discovery that brain …

Clinical studies suggest a link between type 2 diabetes mellitus (T2DM) and insulin
resistance (IR) and cognitive dysfunction, but there are significant gaps in our knowledge of …

Mental processes and their neural substrates are intimately linked to the homeostatic control
of internal bodily state. There are a set of distinct interoceptive pathways that directly and …

The incidence of obesity in middle age is increasing markedly, and in parallel the
prevalence of metabolic disorders including cardiovascular disease and type II diabetes is …

Integrative explanations of why obesity is more prevalent in some sectors of the human
population than others are lacking. Here, we outline and evaluate one candidate …

Poor diet and obesity are associated with cognitive impairment throughout adulthood, and
increased dementia risk in aging. Here we review the current literature interrogating the …

Intake of saturated fats and simple carbohydrates, two of the primary components of a
modern Western diet, is linked with the development of obesity and Alzheimer's Disease …

Obesity is on the rise in all developed countries, and a large part of this epidemic has been
attributed to excess caloric intake, induced by ever present food cues and the easy …

The associations between consumption of a high-fat or 'Western'diet and metabolic
disorders such as obesity, diabetes, and cardiovascular disease have long been recognized …