[HTML][HTML] A review on the potential of Resveratrol in prevention and therapy of diabetes and diabetic complications

DD Huang, G Shi, Y Jiang, C Yao, C Zhu - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Diabetes mellitus (DM) is a major world health problem and one of the most studied
diseases, which are highly prevalent in the whole world, it is frequently associated with …

Diabetic peripheral neuropathy: current perspective and future directions

R Singh, L Kishore, N Kaur - Pharmacological research, 2014 - Elsevier
Diabetic neuropathy is a heterogeneous group of disorders with extremely complex
pathophysiology and affects both somatic and autonomic components of the nervous …

Melatonin modulates neuroinflammation and oxidative stress in experimental diabetic neuropathy: effects on NF‐κB and Nrf2 cascades

G Negi, A Kumar, SS Sharma - Journal of pineal research, 2011 - Wiley Online Library
Melatonin exhibits an array of biological activities, including antioxidant and anti‐
inflammatory actions. Diabetic neuropathy is one of the complications of diabetes with a …

Antioxidant effects of resveratrol in cardiovascular, cerebral and metabolic diseases

A Carrizzo, M Forte, A Damato, V Trimarco… - Food and chemical …, 2013 - Elsevier
Resveratrol—a natural polyphenolic compound—was first discovered in the 1940s.
Although initially used for cancer therapy, it has shown beneficial effects against most …

[HTML][HTML] Resveratrol attenuates testicular apoptosis in type 1 diabetic mice: Role of Akt-mediated Nrf2 activation and p62-dependent Keap1 degradation

Y Zhao, W Song, Z Wang, Z Wang, X Jin, J Xu, L Bai… - Redox biology, 2018 - Elsevier
Infertility is a common complication in diabetic men, mainly due to the loss of germ cells by
apoptotic cell death. However, effective and safe approaches to prevent diabetic induction of …

Impaired adenosine monophosphate-activated protein kinase signalling in dorsal root ganglia neurons is linked to mitochondrial dysfunction and peripheral …

SK Roy Chowdhury, DR Smith, A Saleh, J Schapansky… - Brain, 2012 - academic.oup.com
Mitochondrial dysfunction occurs in sensory neurons and may contribute to distal
axonopathy in animal models of diabetic neuropathy. The adenosine monophosphate …

Mitochondrial dysfunction in diabetic neuropathy: a series of unfortunate metabolic events

P Fernyhough - Current diabetes reports, 2015 - Springer
Diabetic neuropathy is a dying back neurodegenerative disease of the peripheral nervous
system where mitochondrial dysfunction has been implicated as an etiological factor …

Nrf2 and NF-κB modulation by sulforaphane counteracts multiple manifestations of diabetic neuropathy in rats and high glucose-induced changes

G Negi, A Kumar, SS Sharma - Current neurovascular …, 2011 - ingentaconnect.com
High glucose driven reactive oxygen intermediates production and inflammatory damage
are recognized contributors of nerve dysfunction and subsequent damage in diabetic …

NF-κB inhibitory action of resveratrol: a probable mechanism of neuroprotection in experimental diabetic neuropathy

A Kumar, SS Sharma - Biochemical and biophysical research …, 2010 - Elsevier
Resveratrol has shown array of biological actions, and is under clinical development for
various disease conditions. The etiology of diabetic neuropathy revolves around oxidative …

The effect of Polygonum hyrcanicum Rech. f. hydroalcoholic extract on oxidative stress and nephropathy in alloxan-induced diabetic mice

H Arabnozari, F Shaki, A Najjari, F Sharifianjazi… - Scientific Reports, 2024 - nature.com
Diabetic nephropathy, characterized by inflammation and oxidative stress, poses a
management challenge. This study investigates the effect of Polygonum hyrcanicum extract …