The liver is the commonest site of metastatic disease for patients with colorectal cancer, with
at least 25% developing colorectal liver metastases (CRLM) during the course of their …

Hepatocytes are the main workers in the hepatic factory, managing metabolism of nutrients
and xenobiotics, production and recycling of proteins, and glucose and lipid homeostasis …

BACKGROUND: Posthepatectomy liver failure is a feared complication after hepatic
resection and a major cause of perioperative mortality. There is currently no standardized …

Hepatic ischemia reperfusion injury (IRI) is not only a pathophysiological process involving
the liver, but also a complex systemic process affecting multiple tissues and organs. Hepatic …

Abstract Background The Child–Pugh (CP) score is used widely to assess liver function and
predict postoperative outcomes in patients with hepatocellular carcinoma (HCC). Recently …

Cholangiocarcinoma (CCA) is the second most common primary liver malignancy after
hepatocellular carcinoma 1 and arises from the epithelial cells of the intrahepatic and …

Background: Liver resection represents the first choice of treatment for primary and
secondary liver malignancies, offering the patient the best chance of long-term survival. The …

Objective: To review the literature on the most clinically relevant and novel liver function
tests used for the assessment of hepatic function before liver surgery. Background …

Hepatic resection had an impressive growth over time. It has been widely performed for the
treatment of various liver diseases, such as malignant tumors, benign tumors, calculi in the …

Background Liver failure has remained a major cause of mortality after hepatectomy, but it is
difficult to predict preoperatively. This study describes the introduction into clinical practice of …