Recent developments in dynamic kinetic resolution

H Pellissier - Tetrahedron, 2011 - Elsevier
This review updates the principal methods used to obtain dynamic kinetic resolution (DKR)
by either enzymatic or nonenzymatic methods, covering the literature from 2008 to the …

Lipases: Valuable catalysts for dynamic kinetic resolutions

AS de Miranda, LSM Miranda, ROMA de Souza - Biotechnology Advances, 2015 - Elsevier
Dynamic kinetic resolutions have proven to be a useful method for the preparation of
enantiopure compounds from racemates, leading to the formation of a single enantiomer in …

Deracemisation methods

NJ Turner - Current Opinion in Chemical Biology, 2010 - Elsevier
New methods continue to be developed for the dynamic kinetic resolution (DKR) and
deracemisation of racemic chiral compounds, in particular alcohols, amines and amino …

Dynamic kinetic resolution of amines and amino acids by enzyme–metal cocatalysis

Y Kim, J Park, MJ Kim - ChemCatChem, 2011 - Wiley Online Library
Methods for the conversion of racemates to single enantiomers are of great importance in
organic and pharmaceutical chemistry. Enzymatic kinetic resolution has been most …

Chemoenzymatic dynamic kinetic resolution of alcohols and amines

JH Lee, K Han, MJ Kim, J Park - European Journal of Organic …, 2010 - Wiley Online Library
Dynamic kinetic resolution (DKR) is an attractive process for the transformation of racemic
mixtures into optically active compounds. For successful DKR, efficient racemization is …

Photoredox-Driven Three-Component Coupling of Aryl Halides, Olefins, and O2

MC Maust, SB Blakey - ACS catalysis, 2024 - ACS Publications
Modern organic synthesis requires methodologies that bring together abundant feedstock
chemicals in a mild and efficient manner. To aid in this effort, we have developed a …

Dynamic Kinetic Resolution via Hydrolase‐Metal Combo Catalysis in Stereoselective Synthesis of Bioactive Compounds

P Hoyos, V Pace, AR Alcantara - Advanced Synthesis & …, 2012 - Wiley Online Library
The development of new and more economically and environmentally attractive processes
to afford chiral molecules is still an open challenge in organic synthesis. During last years …

Immobilization of Pseudomonas stutzeri lipase through cross-linking aggregates (CLEA) for reactions in deep eutectic solvents

N Guajardo, K Ahumada, PD de María - Journal of Biotechnology, 2021 - Elsevier
The use of deep eutectic solvents (DES) with buffer as cosolvent (up to 10% v/v) leads to low-
viscous media in which lipases can perform synthetic reactions, instead of hydrolysis. This …

Enzymatic Synthesis and Molecular Modelling Studies of Rhamnose Esters Using Lipase from Pseudomonas stutzeri

C García-Oliva, A Perona, Á Rumbero, P Hoyos… - International Journal of …, 2022 - mdpi.com
Rhamnolipids are becoming an important class of glycolipid biosurfactants. Herein, we
describe for the first time the enzymatic synthesis of rhamnose fatty acid esters by the …

Ionic‐Surfactant‐Coated Burkholderia cepacia Lipase as a Highly Active and Enantioselective Catalyst for the Dynamic Kinetic Resolution of Secondary Alcohols

H Kim, YK Choi, J Lee, E Lee, J Park… - Angewandte Chemie …, 2011 - Wiley Online Library
Dynamic kinetic resolution (DKR) is among the most practical methods for the transformation
of racemates to single enantiomers.[1] DKR can provide high yields and excellent …