Over the past decade, the role of the 14–3-3 protein has received increasing interest. Seven
subtypes of 14–3-3 proteins exhibit high homology; however, each subtype maintains its …

Dynein, an ancient microtubule-based motor protein, performs diverse cellular functions in
nearly all eukaryotic cells, with the exception of land plants. It has evolved into three …

Cytoplasmic dynein-driven movement of chromosomes during prophase I of mammalian
meiosis is essential for synapsis and genetic exchange. Dynein connects to chromosome …

Calponin and transgelin (originally named SM22) are homologous cytoskeleton proteins
that regulate actin-activated myosin motor functions in smooth muscle contraction and non …

In animal cells, a single cytoplasmic dynein motor mediates microtubule minus-end-directed
transport, counterbalancing dozens of plus-end-directed kinesins. The remarkable ability of …

Cell division orientation, which is key to cell fate and shaping tissues, is influenced by
mechanical forces. For example, in uniaxially stretched tissue most divisions orient along the …

The conserved exocyst complex regulates plasma membrane-directed vesicle fusion in
eukaryotes. However, its role in stem cell proliferation has not been reported. Germline stem …

Cells within an organism experience a variety of mechanical forces from their surrounding
tissue environment. Reading and responding to these forces is crucial to shape and …

First Person is a series of interviews with the first authors of a selection of papers published
in Journal of Cell Science, helping early-career researchers promote themselves alongside …