Systems metabolic engineering of microorganisms for food and cosmetics production

KR Choi, SY Lee - Nature Reviews Bioengineering, 2023 - nature.com
The demand for sustainable and environmentally friendly sources of foods and cosmetics is
increasing owing to concerns about the rapid growth of the global population and climate …

Research progress on the functions, preparation and detection methods of l-fucose

Y Wang, X Zhang, X Tian, Y Wang, X Xing, S Song - Food Chemistry, 2024 - Elsevier
Abstract l-fucose is a six-carbon sugar that has potential applications in many fields. It exerts
antitumor effects and could relieve intestinal disease. It exhibits potential as an emulsifier in …

Efficient Production of 2′-Fucosyllactose from l-Fucose via Self-Assembling Multienzyme Complexes in Engineered Escherichia coli

L Wan, Y Zhu, G Chen, G Luo, W Zhang… - ACS Synthetic …, 2021 - ACS Publications
2′-Fucosyllactose (2′-FL) has been widely used as a nutritional additive in infant formula
due to its multifarious nutraceutical and pharmaceutical functions in neonate health. As …

Recent advances in a functional deoxy hexose l-fucose: Occurrence, physiological effects, and preparation

J Meng, Y Zhu, N Wang, W Zhang, W Mu - Trends in Food Science & …, 2023 - Elsevier
Background l-Fucose is a functional deoxyhexose prevalent in various organisms.
Particularly, it is the general backbone unit of the polysaccharides of many edible brown …

Multi-enzyme systems and recombinant cells for synthesis of valuable saccharides: advances and perspectives

J Yang, T Zhang, C Tian, Y Zhu, Y Zeng, Y Men… - Biotechnology …, 2019 - Elsevier
Saccharides have recently attracted considerable attention because of their biological
functions and potential applications in the pharmaceutical, cosmetic and food industries …

Regulation on Pathway Metabolic Fluxes to Enhance Colanic Acid Production in Escherichia coli

W Liu, J Peng, S Zou, L Xu, H Cheng… - Journal of Agricultural …, 2023 - ACS Publications
Colanic acid (CA) is a natural polysaccharide macromolecule with rich and unique
biological properties and is a promising candidate for use in food and cosmetics. To date …

Microbial Synthesis of l-Fucose with High Productivity by a Metabolically Engineered Escherichia coli

J Meng, Y Zhu, R Chen, Y Liu, W Zhang… - Journal of agricultural …, 2023 - ACS Publications
l-Fucose is a natural deoxy hexose found in a variety of organisms. It possesses many
physiological effects and has potential applications in pharmaceutical, cosmetic, and food …

Recent advances and challenges in microbial production of human milk oligosaccharides

J Deng, X Lv, J Li, G Du, J Chen, L Liu - Systems Microbiology and …, 2021 - Springer
Human milk oligosaccharides (HMOs) are one of the major differences between livestock
milk and human milk, and the prebiotic functions of HMOs have been verified through in vitro …

High-Level Production of l-Fucose by Plasmid-Free or Antibiotic-Independent Metabolically Engineered Escherichia coli Strains

J Meng, Y Zhu, Z Lu, W Zhang, T Zhang… - ACS Sustainable …, 2024 - ACS Publications
l-Fucose is an important monosaccharide unit that exists in various biomasses, especially in
microalgae. Microbial l-fucose using metabolically engineered strains has attracted attention …

Efficient Biosynthesis of Lacto-N-Biose I, a Building Block of Type I Human Milk Oligosaccharides, by a Metabolically Engineered Escherichia coli

M Tao, L Yang, C Zhao, W Zhang, Y Zhu… - Journal of Agricultural …, 2024 - ACS Publications
Lacto-N-biose I (LNB), termed a Type 1 disaccharide, is an important building block of
human milk oligosaccharides. It shows promising prebiotic activity by stimulating the …