Lactococci and lactobacilli as mucosal delivery vectors for therapeutic proteins and DNA vaccines

LG Bermúdez-Humarán, P Kharrat, JM Chatel… - Microbial cell …, 2011 - Springer
Abstract Food-grade Lactic Acid Bacteria (LAB) have been safely consumed for centuries by
humans in fermented foods. Thus, they are good candidates to develop novel oral vectors …

The emerging role of probiotics as a mitigation strategy against coronavirus disease 2019 (COVID-19)

R Mirzaei, A Attar, S Papizadeh, AS Jeda… - Archives of …, 2021 - Springer
COVID-19 is an acute respiratory infection accompanied by pneumonia caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which has affected millions of …

Does Lactobacillus Exert a Protective Effect on the Development of Cervical and Endometrial Cancer in Women?

K Frąszczak, B Barczyński, A Kondracka - Cancers, 2022 - mdpi.com
Simple Summary Cervical cancer is the fourth most common cancer in women worldwide.
Tumour-related deaths are most frequent in low-and middle-income countries. Currently …

Cross‐talk between probiotic lactobacilli and host immune system

TS Kemgang, S Kapila… - Journal of applied …, 2014 - academic.oup.com
The mechanism by which probiotic lactobacilli affect the immune system is strain specific. As
the immune system is a multicompartmental system, each strain has its way to interact with it …

Gastrointestinal involvement in SARS-CoV-2 infection

TH Chen, MT Hsu, MY Lee, CK Chou - Viruses, 2022 - mdpi.com
SARS-CoV-2 has evolved into a virus that primarily results in mild or asymptomatic disease,
making its transmission more challenging to control. In addition to the respiratory tract, SARS …

The year that shaped the outcome of the OspA vaccine for human Lyme disease

RJ Dattwyler, M Gomes-Solecki - Npj Vaccines, 2022 - nature.com
The expansion of Lyme borreliosis endemic areas and the corresponding increase of
disease incidence have opened the possibility for greater acceptance of a vaccine. In this …

Design of a broadly reactive Lyme disease vaccine

HD Kamp, KA Swanson, RR Wei, PK Dhal… - npj Vaccines, 2020 - nature.com
A growing global health concern, Lyme disease has become the most common tick-borne
disease in the United States and Europe. Caused by the bacterial spirochete Borrelia …

Mucosal vaccination and therapy with genetically modified lactic acid bacteria

J Wells - Annual review of food science and technology, 2011 - annualreviews.org
Lactic acid bacteria (LAB) have proved to be effective mucosal delivery vehicles that
overcome the problem of delivering functional proteins to the mucosal tissues. By the …

Probiotic-based vaccines may provide effective protection against COVID-19 acute respiratory disease

S Taghinezhad-S, AH Mohseni… - Vaccines, 2021 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 virus (SARS-CoV-2) infection, the
causative agent of COVID-19, now represents the sixth Public Health Emergency of …

A recombinant Lactobacillus plantarum strain expressing the spike protein of SARS-CoV-2

M Wang, T Fu, J Hao, L Li, M Tian, N Jin, L Ren… - International journal of …, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19), which is caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global pandemic in the …