[HTML][HTML] Circulating tumor DNA: a promising biomarker in the liquid biopsy of cancer

F Cheng, L Su, C Qian - Oncotarget, 2016 - ncbi.nlm.nih.gov
Tissue biopsy is the standard diagnostic procedure for cancers and also provides a material
for genotyping, which can assist in the targeted therapies of cancers. However, tissue biopsy …

Liquid biopsies based on DNA methylation as biomarkers for the detection and prognosis of lung cancer

P Li, S Liu, L Du, G Mohseni, Y Zhang, C Wang - Clinical epigenetics, 2022 - Springer
Lung cancer (LC) is the main cause of cancer-related mortality. Most LC patients are
diagnosed in an advanced stage when the symptoms are obvious, and the prognosis is …

Lengthening and shortening of plasma DNA in hepatocellular carcinoma patients

P Jiang, CWM Chan, KCA Chan… - Proceedings of the …, 2015 - National Acad Sciences
The analysis of tumor-derived circulating cell-free DNA opens up new possibilities for
performing liquid biopsies for the assessment of solid tumors. Although its clinical potential …

Prognostic significance of blood-based multi-cancer detection in plasma cell-free DNA

X Chen, Z Dong, E Hubbell, KN Kurtzman… - Clinical Cancer …, 2021 - AACR
Purpose: We recently reported the development of a cell-free DNA (cfDNA) targeted
methylation (TM)-based sequencing approach for a multi-cancer early detection (MCED) test …

DNA methylation-based testing in liquid biopsies as detection and prognostic biomarkers for the four major cancer types

V Constâncio, SP Nunes, R Henrique, C Jerónimo - Cells, 2020 - mdpi.com
Lung, breast, colorectal, and prostate cancers are the most incident worldwide. Optimal
population-based cancer screening methods remain an unmet need, since cancer detection …

Liquid biopsy in hepatocellular carcinoma: circulating tumor cells and circulating tumor DNA

Q Ye, S Ling, S Zheng, X Xu - Molecular cancer, 2019 - Springer
Hepatocellular carcinoma (HCC) is one of the most common cancers and a leading cause of
death worldwide. Due to latent liver disease, late diagnosis, and nonresponse to systemic …

Liquid biopsy: a distinctive approach to the diagnosis and prognosis of cancer

T Hirahata, R ul Quraish, A Quraish… - Cancer …, 2022 - journals.sagepub.com
Cancer is a leading cause of morbidity and mortality worldwide. Over the past decades, the
concept of precision cancer medicine has emerged as a novel approach in the field of …

Detection and relevance of epigenetic markers on ctDNA: recent advances and future outlook

E Lianidou - Molecular Oncology, 2021 - Wiley Online Library
Liquid biopsy, a minimally invasive approach, is a highly powerful clinical tool for the real‐
time follow‐up of cancer and overcomes many limitations of tissue biopsies. Epigenetic …

Cancer epigenetic biomarkers in liquid biopsy for high incidence malignancies

C Palanca-Ballester, A Rodriguez-Casanova, S Torres… - Cancers, 2021 - mdpi.com
Simple Summary Apart from genetic changes, cancer is characterized by epigenetic
alterations, which indicate modifications in the DNA (such as DNA methylation) and histones …

Methylated circulating tumor DNA in blood: power in cancer prognosis and response

K Warton, KL Mahon, G Samimi - Endocrine-related cancer, 2016 - erc.bioscientifica.com
The aim of the present study was to perform a systematic review of published studies to
provide a robust estimation of the use of procalcitonin (ProCT) as a diagnostic marker of …